877130-14-8 - Names and Identifiers
877130-14-8 - Physico-chemical Properties
877130-14-8 - Introduction
2-(4-Bromo-2-fluorophenyl)propan-2-amine is an organic compound with the chemical formula C9H12BrFN. The following is a description of the properties, uses, preparation and safety information of this compound:
Nature:
-Appearance: Colorless to light yellow liquid or solid.
-Melting point: About 45-48 degrees Celsius.
-Boiling point: About 173-175 degrees Celsius.
-Density: about 1.42 g/mL.
-Solubility: Soluble in organic solvents such as ethanol, dimethylformamide and dichloromethane.
Use:
2-(4-Bromo-2-fluorophenyl)propan-2-amine can be used as catalysts in organic synthesis reactions, pharmaceutical intermediates and other chemical fields. Specific applications include pharmaceutical research, Pesticide Synthesis and dye synthesis.
Method:
The preparation of 2-(4-Bromo-2-fluorophenyl)propan-2-amine is generally achieved by a carbon-carbon bond formation reaction. Specific steps include:
1.4-bromo -2-fluorobenzaldehyde and propylamine are reacted under alkaline conditions to generate 4-bromo -2-fluorophenyl propylamine.
2. The product reacts with a chemical reducing agent such as sulfurous acid or hypochlorite to reduce and generate the target product 2-(4-Bromo-2-fluorophenyl)propan-2-amine.
Safety Information:
- 2-(4-Bromo-2-fluorophenyl)propan-2-amine is an organic compound, and you need to pay attention to protective measures when using it, such as wearing gloves and goggles.
-During operation, avoid contact with the skin and inhalation of dust or steam from the compound.
-Irritating to eyes, avoid contact with eyes, and immediately rinse the affected area with plenty of water.
-When storing and handling, keep away from ignition sources and other materials that are prone to Sparks to avoid fire and explosion.
Last Update：2024-04-09 19:05:55