879275-77-1 - Names and Identifiers
Name | benzyl N-[(3R)-pyrrolidin-3-yl]carbamate
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Synonyms | (R)-3-N-Cbz-Aminopyrrolidine (R)-benzyl pyrrolidin-3-ylcarbamate Benzyl (3R)-pyrrolidin-3-ylcarbamate benzyl N-[(3R)-pyrrolidin-3-yl]carbamate CarbaMic acid,N-(3R)-3-pyrrolidinyl-, phenylMethyl ester Carbamic acid, N-[(3R)-3-pyrrolidinyl]-, phenylmethyl ester
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CAS | 879275-77-1
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InChI | InChI=1/C12H16N2O2/c15-12(14-11-6-7-13-8-11)16-9-10-4-2-1-3-5-10/h1-5,11,13H,6-9H2,(H,14,15)/t11-/m1/s1 |
879275-77-1 - Physico-chemical Properties
Molecular Formula | C12H16N2O2
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Molar Mass | 220.27 |
Density | 1.16g/cm3 |
Boling Point | 382.5°C at 760 mmHg |
Flash Point | 185.1°C |
Vapor Presure | 4.69E-06mmHg at 25°C |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Refractive Index | 1.564 |
879275-77-1 - Introduction
Benzyl N-[(3R)-pyrrolidin-3-yl]carbamate, also known as benzyl N-[(3R)-pyrrolidin-3-yl]carbamate, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
The compound has a molecular formula of C15H20N2O2 and a relative molecular mass of 260.33. It is solid and has a white or off-white appearance. Its melting point is typically between about 80-85 degrees Celsius. This compound is chiral and exists as the (R)-stereoisomer.
Use:
benzyl N-[(3R)-pyrrolidin-3-yl]carbamate is a common organic synthesis intermediate. It is often used as a starting material in the preparation of other compounds. This compound plays an important role in the synthesis of organic compounds, such as bioactive molecules, pharmaceuticals and pesticides.
Preparation Method:
The preparation of benzyl N-[(3R)-pyrrolidin-3-yl]carbamate is usually carried out by chemical synthesis methods. A common method of preparation is to react (R)-3-aminopyrrolidine with benzylchloroformate to form the desired product. Further manipulations may involve steps of crystallization, purification and drying.
Safety Information:
When handling benzyl N-[(3R)-pyrrolidin-3-yl]carbamate, the following safety precautions should be paid attention to: Use gloves and safety glasses to avoid contact with skin and eyes. Maintain a well-ventilated environment during operation and avoid inhaling dust or gas. If skin contact or ingestion occurs, wash the affected area immediately or seek professional medical help. During storage, the compound should be placed in a cold and dark place, away from flammable materials and oxidants.
Please note that the information provided here is for reference only. For specific operations, please refer to the relevant literature on the compound and follow laboratory or industrial safety procedures.
Last Update:2024-04-09 15:18:00