883-44-3

883-44-3 - Names and Identifiers

Name	N-(3-hydroxypropyl)phthalimide
Synonyms	AURORA 4786 3-Phthalimidopropanol 3-PHTHALIMIDO-1-PROPANOL N-(3-hydroxypropyl)phthalimide N-(3-HYDROXYPROPYL)PHTHALIMIDE 2-(3-Hydroxypropyl)isoindoline-1,3-dione 2-(3-Hydroxypropyl)-2H-isoindole-1,3-dione 2-(3-Hydroxypropyl)-1H-isoindole-1,3(2H)-dione 2-(3-hydroxypropyl)-1H-isoindole-1,3(2H)-dione 2-(3-hydroxypropyl)-2,3-dihydro-1H-isoindole-1,3-dione
CAS	883-44-3
EINECS	212-931-1
InChI	InChI=1/C11H11NO3/c13-7-3-6-12-10(14)8-4-1-2-5-9(8)11(12)15/h1-2,4-5,13H,3,6-7H2

883-44-3 - Physico-chemical Properties

Molecular Formula	C11H11NO3
Molar Mass	205.21
Density	1.331±0.06 g/cm3(Predicted)
Melting Point	74-76 °C (lit.)
Boling Point	376.5±25.0 °C(Predicted)
Flash Point	181.5°C
Vapor Presure	2.44E-06mmHg at 25°C
Appearance	Crystalline Powder
Color	White
BRN	158489
pKa	14.88±0.10(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.605
MDL	MFCD00023097

883-44-3 - Risk and Safety

Safety Description	24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29251900

883-44-3 - Introduction

N-(3-hydroxypyl) phthalimide is an organic compound with the chemical formula C10H11NO3. It is a white or off-white solid, soluble in alcohol and ether, slightly soluble in water.

N-(3-hydroxypropyl)phthalimide are commonly used as reagents or intermediates in organic synthesis. It can be used as a protective agent for carboxylic acids in many reactions, by reacting with carboxylic acids to form esters, which are then removed by heating or acidolysis reactions. In addition, it can also be used as a polymer modifier and amine activator.

The preparation method of N-(3-hydroxypropyl)phthalimide is relatively simple. One common method of preparation is to react phthalic acid with 3-hydroxypropanol. First, phthalic acid is reacted with sodium hydroxide under basic conditions to form the corresponding sodium salt. The sodium salt is then reacted with 3-hydroxypropanol under basic conditions to produce N-(3-hydroxypropyl)phthalimide. Finally, it is precipitated from the reaction system by acidification.

Regarding safety information, the N-(3-hydroxypyl) phthalimide should be used with caution. It may be irritating to the eyes, skin and respiratory tract, so care should be taken to avoid contact when using it. At the same time, further evaluation and experimental verification are needed for other potential risks. In order to use the compound safely, the operation should follow the safety procedures, and take appropriate personal protective measures, such as wearing gloves, goggles, etc. Before use, it is best to read the product-related safety data form for detailed safety information.

Last Update：2024-04-10 22:29:15