88335-93-7

88335-93-7 - Names and Identifiers

Name	(1S,2R)-1-methyl cis-1,2,3,6-tetrahydro-phthalate
Synonyms	6-MCCA (1S,2R)-1-METHYL CIS-1,2,3,6-TETRAHYDROPHTHALATE (1S,2R)-1-methyl cis-1,2,3,6-tetrahydro-phthalate 6-Methoxycarbonyl-3-cyclohexene-1-carboxylic acid 6-methoxycarbonyl-3-cyclohexene-1-carboxylic acid 6-(methoxycarbonyl)cyclohex-3-ene-1-carboxylic acid 6-(Methoxycarbonyl)cyclohex-3-ene-1-carboxylic acid 1-METHYL (1S,2R)-(+)-CIS-1,2,3,6-TETRAHYDROPHTHALATE (1S,2R)-1-METHYL CIS-4-CYCLOHEXENE-1,2-DICARBOXYLATE (1R,6S)-6-methoxycarbonylcyclohex-3-ene-1-carboxylic acid (1R,6S)-6-(Methoxycarbonyl)cyclohex-3-ene-1-carboxylic acid (1S,2R)-4-Cyclohexene-1,2-dicarboxylic acid monomethyl ester (1S,2R)-cis-Cyclohex-4-ene-1,2-dicarboxylic 1-monomethyl ester (1R,6S)-cis-6-(Methoxycarbonyl)cyclohex-3-ene-1-carboxylic acid (1S,2R)-CIS-4-CYCLOHEXENE-1,2-DICARBOXYLIC ACID 1-MONOMETHYL ESTER (1S,2R)-cis-4-Cyclohexene-1,2-dicarboxylic acid 1-monomethylester, (1S,2R)-1-Methyl cis-4-cyclohexene-1,2-dicarboxylate
CAS	88335-93-7
InChI	InChI=1/C9H12O4/c1-13-9(12)7-5-3-2-4-6(7)8(10)11/h2-3,6-7H,4-5H2,1H3,(H,10,11)/t6-,7+/m1/s1

88335-93-7 - Physico-chemical Properties

Molecular Formula	C9H12O4
Molar Mass	184.19
Density	1.231
Melting Point	65-67°C(lit.)
Boling Point	306.5±42.0 °C(Predicted)
Specific Rotation(α)	13 º (c=1, acetone)
Flash Point	121°C
Water Solubility	Insoluble in water.
Vapor Presure	0mmHg at 25°C
BRN	5262096
pKa	4.26±0.40(Predicted)
Storage Condition	2-8℃
Refractive Index	1.504
MDL	MFCD00075490

88335-93-7 - Risk and Safety

WGK Germany

88335-93-7 - Introduction

(1S, 2R)-4-cyclohexene-1, 6-dicarboxylic acid monomethyl ester, chemical formula C9H12O4, molecular weight 184.19g/mol.

Properties:(1S, 2R)-4-cyclohexene-1, 6-dicarboxylic acid monomethyl ester is a colorless or light yellow liquid with a special fragrance at room temperature. It can be dissolved in certain organic solvents, such as ethanol and ether.

Purpose:(1S, 2R)-4-cyclohexene-1, 6-dicarboxylic acid monomethyl ester is an important chemical intermediate, widely used in medicine, pesticide, spice and dye industry. It can be used to synthesize a variety of drugs and bioactive molecules, such as cyclazolone antibiotics, anticancer drugs, etc.

Preparation:(1S, 2R)-4-cyclohexene-1, 6-dicarboxylic acid monomethyl ester is generally prepared by reacting (1S, 2R)-4-cyclohexene-1, 2,3, 6-tetra-carboxylic acid methyl ester with a suitable reducing agent. Specifically, methyl (1S, 2R)-4-cyclohexene-1, 2,3, 6-tetra-carboxylate is reacted with a reducing agent such as sodium borohydride at an appropriate temperature to obtain monomethyl (1S, 2R)-4-cyclohexene-1, 6-dicarboxylate.

Safety information:(1S, 2R)-4-cyclohexene-1, 6-dicarboxylic acid monomethyl ester is relatively safe under general operating conditions. But it can be irritating to the eyes and skin, and can be potentially chronic toxic to humans. Therefore, when using and handling, appropriate personal protective measures should be taken, such as wearing gloves, goggles and protective clothing. At the same time, the relevant laws and regulations should be followed and the correct storage and handling of the chemical should be ensured.

Last Update：2024-04-09 21:11:58