Molecular Formula | C9H7IN2O2 |
Molar Mass | 302.07 |
Density | 1.948±0.06 g/cm3(Predicted) |
Boling Point | 421.4±25.0 °C(Predicted) |
Appearance | Crystalline powder |
pKa | 10.47±0.40(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
MDL | MFCD07781616 |
Hazard Symbols | T - Toxic |
Risk Codes | 25 - Toxic if swallowed |
Safety Description | 45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
WGK Germany | 3 |
application | 3-iodoindazole -6-methyl formate is an indazole compound, which is widely used in the fields of medicine and chemical industry. |
preparation | 3.0g(17.0 mmol) of 1H-indazole -6-methyl formate, 50 mL of methanol and 0.8g(20.0 mmol) of sodium hydroxide were sequentially added into the reaction bottle, and stirred to dissolve it. 5.2g(20.0mmol) of iodine was added in batches at room temperature and finished (0.5 hours), reaction 1 hours (TLC monitors the progress of the reaction until the reaction is complete). Filter, evaporate the filtrate to dry, add 45 mL of saturated sodium sulfite solution, stir for 0.5 hours (precipitate solid), filter, and dry the filter cake to obtain light yellow solid 3-iodoindazole -6-methyl formate. |