886496-88-4

886496-88-4 - Names and Identifiers

Name	3-bromo-4-(trifluoromethoxy)phenol
Synonyms	3-Bromo-4-trifluoromethoxyphenol 3-bromo-4-(trifluoromethoxy)phenol 3-Bromo-4-(trifluoromethoxy)phenol Phenol,3-bromo-4-(trifluoromethoxy)- Phenol, 3-bromo-4-(trifluoromethoxy)-
CAS	886496-88-4
InChI	InChI=1/C7H4BrF3O2/c8-5-3-4(12)1-2-6(5)13-7(9,10)11/h1-3,12H

886496-88-4 - Physico-chemical Properties

Molecular Formula	C7H4BrF3O2
Molar Mass	257
Density	1.779±0.06 g/cm3(Predicted)
Boling Point	233.5±35.0 °C(Predicted)
Flash Point	95°C
Vapor Presure	0.0365mmHg at 25°C
pKa	8.39±0.18(Predicted)
Storage Condition	2-8℃
Refractive Index	1.506

886496-88-4 - Introduction

3-bromo-4-(trifluoromethoxy)phenol is an organic compound with the chemical formula C7H4BrF3O.

Nature:
-Appearance: 3-bromo-4-(trifluoromethoxy)phenol is a colorless or slightly yellow solid.
-Melting point: about 60-65°C.
-Boiling point: about 220-225°C.
-Solubility: It has good solubility in common organic solvents.

Use:
- 3-bromo-4-(trifluoromethoxy)phenol is commonly used as a pharmaceutical intermediate. It can be used in the synthesis of other organic compounds, such as pesticides, fungicides and antibacterial drugs.
-In biological sciences, it can also be used as a dye or indicator.

Preparation Method:
3-bromo-4-(trifluoromethoxy)phenol has many preparation methods, and a common method is obtained by reacting p-bromophenol with trifluoromethane anhydride. The specific steps are as follows:
1. Add bromophenol and trifluoromethane anhydride to the reaction flask.
2. Add a certain amount of acidic catalyst (such as sulfuric acid).
3. Stir the reaction mixture at a lower temperature and react for a period of time.
4. Adjust the pH and separate the product from the mixture.
5. refining and crystallization of purified product.

Safety Information:
- 3-bromo-4-(trifluoromethoxy)phenol is irritating and may be harmful to the eyes and skin. Pay attention to protective measures and wear appropriate personal protective equipment when using.
-During use and storage, keep away from ignition and other oxidants.
-Avoid inhaling its dust or vapor during operation, and ensure that it is operated in a well-ventilated place.
-Please handle and dispose of waste properly in accordance with relevant regulations.

Last Update：2024-04-09 02:00:48