886593-45-9

886593-45-9 - Names and Identifiers

Name	4-(2-hydroxypropan-2-yl)phenylboronic acid
Synonyms	4-(2-Hydroxy-2-propanyl)phenylboronic Acid 4-(2-hydroxypropan-2-yl)phenylboronic acid [4-(2-Hydroxy-2-propanyl)phenyl]boronic acid B-[4-(1-hydroxy-isopropyl)phenyl]boronic acid [4-(1-Hydroxy-1-methylethyl)phenyl]boronic acid Boronic acid, [4-(1-hydroxy-1-methylethyl)phenyl]- Boronic acid, B-[4-(1-hydroxy-1-methylethyl)phenyl]-
CAS	886593-45-9
InChI	InChI=1S/C9H13BO3/c1-9(2,11)7-3-5-8(6-4-7)10(12)13/h3-6,11-13H,1-2H3

886593-45-9 - Physico-chemical Properties

Molecular Formula	C9H13BO3
Molar Mass	180.01
Density	1.16±0.1 g/cm3(Predicted)
Boling Point	354.4±44.0 °C(Predicted)
pKa	8.66±0.17(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

886593-45-9 - Introduction

4-(2-hydroxypropan-2-yl)phenylboronic acid is an organoboron compound. Its chemical formula is C10H13BO3 and its relative molecular mass is 182.02g/mol.

Nature:
4-(2-hydroxypropan-2-yl)phenylboronic acid is a white crystalline solid. It is soluble in water and also soluble in organic solvents. It has a relatively low melting and boiling point, with a melting point of about 100-102°C. It is a stable compound that is not easily oxidized or decomposed.

Use:
4-(2-hydroxypropan-2-yl)phenylboronic acid is an important reagent in organic synthesis. It can be used in phenylboronic acid coupling reactions to form carbon-boron bonds by reacting with organometallic compounds to build complex organic molecular structures. It can also be used as a catalyst ligand to participate in various organic synthesis reactions such as redox reactions, coupling reactions, and cross-coupling reactions.

Preparation Method:
4-(2-hydroxypropan-2-yl)phenylboronic acid can be prepared by the reaction of phenylboronic acid and 2-hydroxypropane. A commonly used preparation method is to react phenylboronic acid with 2-hydroxypropanol under alkaline conditions to produce the target product, which is purified by crystallization to obtain the pure product.

Safety Information:
4-(2-hydroxypan-2-yl) phenylboronic acid is relatively safe under normal conditions of use. However, like any chemical, you should pay attention to safe handling measures, avoid contact with skin, eyes and mouth, and avoid inhaling its dust or vapor. Wear protective gloves, goggles and protective clothing during use. If touched or inhaled, wash the affected area immediately and seek medical advice.

Last Update：2024-04-10 22:29:15