ChemBK
  • Home
  • Product Category

89-98-5

2-Chlorobenzaldehyde

CAS: 89-98-5

Molecular Formula: C7H5ClO

  1. Home
  2. Product Category
  3. Organic raw materials
  4. Aldehydes
  5. 89-98-5

89-98-5 - Names and Identifiers

Name 2-Chlorobenzaldehyde
Synonyms OCAD
OCBA
2-Chlorobenzaldehyde
O-CHLOROBENZALDEHYDE
Amlodipine Impurity T
2 chloro benzaldehyde
Chlorobenzaldehyde, 2-
ortho-chlorobenzaldehyde
ORTHO CHLORO BENZALDEHYDE
2-CHLOROBENZALDEHYDE, DIST.
OCBA(2-Chlorobenzaldehyde )
2-chlorobenzaldehyde radical
O-chlorobenzenecarboxyaldehyde
2-ChlorobenzaldehydeForSynthesis
o-Chlorobenzaldehyde 2-Chlorobenzaldehyde
CAS 89-98-5
EINECS 201-956-3
InChI InChI=1/C7H5ClO/c8-7-4-2-1-3-6(7)5-9/h1-5H

89-98-5 - Physico-chemical Properties

Molecular FormulaC7H5ClO
Molar Mass140.57
Density1.248 g/mL at 25 °C (lit.)
Melting Point9-11 °C (lit.)
Boling Point209-215 °C (lit.)
Flash Point190°F
Water Solubility0.1-0.5 g/100 mL at 24 ºC
Solubility 1.8g/l
Vapor Presure1.27 mm Hg ( 50 °C)
Vapor Density4.84 (vs air)
AppearanceLiquid
ColorClear colorless to light yellow
BRN385877
PH2.9 (H2O)(saturated aqueous solution)
Storage ConditionStore in RT
StabilityStable. Combustible. Incompatible with strong oxidizing agents, strong bases, iron, strong reducing agents. Moisture and light-sensitive.
SensitiveAir Sensitive
Refractive Indexn20/D 1.566(lit.)
Physical and Chemical PropertiesColorless or pale yellow oily liquid. Melting point 12.39 ℃(11 ℃), boiling point 211.9 ℃(213-214 ℃),84.3 ℃(1.33kPa), relative density 1.2483(20/4 ℃), refractive index 1.5662. Flash point 87. Slightly soluble in water, soluble in ethanol, ether, acetone and benzene. There is a strong aldehyde odor.
UseUsed as dye, pesticide, pharmaceutical intermediates

89-98-5 - Risk and Safety

Risk Codes34 - Causes burns
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDsUN 3265 8/PG 3
WGK Germany1
RTECSCU5075000
FLUKA BRAND F CODES8-9-23
TSCAYes
HS Code29130000
Hazard NoteIrritant
Hazard Class8
Packing GroupIII
ToxicityLD50 orally in Rabbit: 2160 mg/kg

89-98-5 - Upstream Downstream Industry

Raw Materials2-Chlorotoluene
2-Chlorotoluene
Chlorine
Downstream Products2-Chloro-5-nitrobenzaldehyde
Clofentezine

89-98-5 - Reference Information

LogP2.44 at 25℃
NIST chemical information information provided by: webbook.nist.gov (external link)
EPA chemical substance information information provided by: ofmpeb.epa.gov (external link)
Use M-chlorobenzaldehyde is an intermediate of the plant growth regulator indyl ester.
It is used as intermediate of medicine and dye. The dead Net of pesticide mites produced by O-chlorobenzaldehyde can control the mites on dry crops and fruit trees. O-chlorobenzoxime can be obtained by O-chlorobenzoxime oximation, and O-chlorobenzoxime can be obtained by further chlorination, which are all drug intermediates.
used as dye, pesticide, pharmaceutical intermediate
used as dye intermediate, also used in organic synthesis
O-chlorobenzaldehyde, also known as 2-chlorobenzaldehyde, is the raw material for the synthesis of acaricide tetrarazine, it can also be used for the synthesis of another new acaricide, new species of fluxazine, and can also be used as a pharmaceutical, dye intermediate.
important pharmaceutical, fuel and pesticide intermediates. It is mainly used in medicine for synthesis of ampicillin (Cloxacillin).
zinc plating brightener, mainly used in the manufacture of O-chlorobenzenes, O-chlorobenzenes chloride and chlorbenzoxazole penicillin sodium and other pharmaceutical raw materials, is also widely used in the manufacture of pesticides on the high-efficiency acaricide, raw materials for dead-clean products of mites.
determination of sorbitol. Preparation of triphenylmethane. Dye Intermediates.
production methods O-chlorobenzaldehyde has the following 3 synthetic methods. (1) O-chlorotoluene chlorination, hydrolysis method from O-chlorotoluene by chlorination, hydrolysis and. (1) chlorination O-chlorotoluene, phosphorus trichloride and thionyl chloride are heated to 150 ° C., and chlorine gas is passed to a theoretical amount under ultraviolet irradiation to obtain O-chlorobenzylidene dichloride. (2) ice solution the mixture of O-chlorobenzylidene dichloride and zinc chloride is heated at 120~130 ℃, and 1% ferric chloride aqueous solution is added dropwise with stirring, then heated and refluxed with water, the separated oil layer is refined O-chlorobenzaldehyde. In addition, the hydrolysis may also be performed in the presence of sulfuric acid. Stir O-chlorobenzylidene dichloride and industrial concentrated sulfuric acid together, and slowly heat for 12h to keep the temperature at 30~40 ℃ until the temperature is automatically lowered and the evolution of hydrogen chloride is slowed down, after stratification with cold water, the oily matter is separated, washed and distilled by steam to obtain the finished product. (2) O-chlorotoluene chlorination, oxidation of O-chlorotoluene in the methyl chloride after nitric acid oxidation. To a 3.0 ML Photo-reactor equipped with a thermometer, a stirrer, a chlorine gas blowing tube, a reflux condenser and a high-pressure mercury lamp illumination device, 380g (130 mol) of O-chlorotoluene was added and heated to ° C, under the light, the chlorine gas was blown into 1.5G/h (3.6 mol/h), and the time was h. A total of 5.4mol chlorine gas was introduced. After completion of the reaction, dry nitrogen was introduced into the reaction solution to drive out hydrogen chloride and chlorine gas to obtain a total of 558g of reaction solution, Among them, O-chlorotoluene 0.5%(mol), O-chlorobenzyl chloride 28%, O-chloro dichlorotoluene 67%, O-chloro trichlorotoluene 3%, O-chloro-chlorotoluene the average degree of chlorination is 1.8. To a 2 L three-necked flask with thermometer, stirrer and reflux condenser, add 64.7g(0.343mol), 3%(mass fraction) of the above chlorinated mixture of O-chlorotoluene. 1440g of nitric acid and 2.0g of vanadium pentoxide were heated under reflux for 6h with stirring. After completion of the reaction, the reaction mixture was cooled, 200ml of toluene was added, the oil phase was separated, and the aqueous layer was extracted twice by adding 100ml of toluene. The oil phase and the extract were combined, toluene was distilled off, and the residue was distilled to obtain 36g of O-chlorobenzaldehyde from the 107~110 ℃(4.0kPa) fraction, with a yield of 73.5% based on O-chlorotoluene. (3) O-chloro-dichlorotoluene was prepared by Catalytic Hydrolysis of O-chloro-dichlorotoluene. Preparation example 1 0.034g of zinc oxide (1mol of raw material, 0.00084mol) was added to 97.7g of O-chlorotoluene, heated to 110 °c with stirring, and then 9.45ml of water was added slowly, the reaction was carried out at 110-120 ℃ for 1.9h. After analysis and confirmation that the raw material O-chloro-dichlorotoluene completely disappeared, vacuum distillation was carried out under a nitrogen stream to collect a fraction at 97.1-98.3 ° C. (2.8kPa) to obtain 68.6g of O-chlorobenzaldehyde, with a yield of 97.6% and a content of 99.8%. Preparation example 2 O-chloro dichlorotoluene 0.3g/min and water vapor 3g/min were added dropwise to the reactor, and 110 of water was added to the reactor in advance, and the water temperature was °c. The resulting mixture of O-chloro-dichlorotoluene and water vapor was passed through a reaction tube layer of 50g of 5-10 mesh trialumina which had been heated to 118 ° C., and the resulting gas was cooled to obtain a suspension, which was extracted with diethyl ether and dried, the ether was distilled off and distilled under reduced pressure under a nitrogen stream to collect fractions at 96-98 ° C. (2.93kPa) to obtain 68.8g of O-chlorobenzaldehyde, with a yield of 95.7% and a content of 97.8%.
The O-chlorotoluene side chain by chlorine and phosphorus trichloride chlorination process, Catalytic Hydrolysis, distillation refined.
The preparation method is to use benzaldehyde as a raw material, add a small amount of aluminum trichloride in the solvent dichloroethane as a catalyst for chlorination, and the reaction temperature is 25-30 ° C. To obtain the product. It can also be prepared by chlorination and hydrolysis of M-chlorotoluene.
category toxic substances
toxicity grade poisoning
Acute toxicity oral-rat LD50: 2160 mg/kg; Oral-mouse LD50: 1900 mg/kg
flammability hazard characteristics toxic chloride fumes from thermal decomposition
storage and transportation characteristics low temperature ventilation and drying
extinguishing agent water, carbon dioxide, foam, dry powder
spontaneous combustion temperature 746 ° F.
toxic substance data information provided by: pubchem.ncbi.nlm.nih.gov (external link)
Last Update：2024-04-09 15:16:53
89-98-5
Supplier List
JIANGSU BSECHEM CHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: 2-Chlorobenzaldehyde Request for quotation
CAS: 89-98-5
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685 Click to send a QQ messageSend QQ message
Nantong Reform Petro-Chemical CO., LTD.
Multiple SpecificationsSpot supply
Product Name: 2-Chlorobenzaldehyde Request for quotation
CAS: 89-98-5
Tel: +86-17551318830
Email: r@reformchem.com­
Mobile: +86-17551318830
QQ: 3785839865 Click to send a QQ messageSend QQ message
Jiangsu Pules Biotechnology Co.,Ltd.
Product Name: 2-Chlorobenzaldehyde Request for quotation
CAS: 89-98-5
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Hubei YoungXin Pharmaceutical Tech Co.,Ltd.
Spot supply
Product Name: Clopidogrel Impurity 20 Visit Supplier Webpage Request for quotation
CAS: 89-98-5
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052 Click to send a QQ message
Wechat: 15671228036
Guangzhou Yuanda New Material Co.,Ltd
Product Name: 2-Chlorobenzaldehyde Request for quotation
CAS: 89-98-5
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589 Click to send a QQ message
Wechat: +86 19849939632
Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: 2-Chlorobenzaldehyde Request for quotation
CAS: 89-98-5
Tel: 0086-551-65418684
Email: sales@tnjchem.com
　　　　 info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Shanghai Worldyang Chemical Co.,Ltd.
Multiple Specifications
Product Name: O-chlorobenzaldehyde Request for quotation
CAS: 89-98-5
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228 Click to send a QQ message
Wechat: 13651600618
WhatsApp: +8613651600618
Orange Petrochemical (Zhejiang Free Trade Zone) Co., Ltd.
Product Name: 2-Chlorobenzaldehyde Request for quotation
CAS: 89-98-5
Tel:
Email: xiehao966@gmail.com
Mobile: 86 15032869000
JIANGSU BSECHEM CHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: 2-Chlorobenzaldehyde Request for quotation
CAS: 89-98-5
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685 Click to send a QQ messageSend QQ message
Nantong Reform Petro-Chemical CO., LTD.
Multiple SpecificationsSpot supply
Product Name: 2-Chlorobenzaldehyde Request for quotation
CAS: 89-98-5
Tel: +86-17551318830
Email: r@reformchem.com­
Mobile: +86-17551318830
QQ: 3785839865 Click to send a QQ messageSend QQ message
Jiangsu Pules Biotechnology Co.,Ltd.
Product Name: 2-Chlorobenzaldehyde Request for quotation
CAS: 89-98-5
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Hubei YoungXin Pharmaceutical Tech Co.,Ltd.
Spot supply
Product Name: Clopidogrel Impurity 20 Visit Supplier Webpage Request for quotation
CAS: 89-98-5
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052 Click to send a QQ message
Wechat: 15671228036
Guangzhou Yuanda New Material Co.,Ltd
Product Name: 2-Chlorobenzaldehyde Request for quotation
CAS: 89-98-5
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589 Click to send a QQ message
Wechat: +86 19849939632
Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: 2-Chlorobenzaldehyde Request for quotation
CAS: 89-98-5
Tel: 0086-551-65418684
Email: sales@tnjchem.com
　　　　 info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Shanghai Worldyang Chemical Co.,Ltd.
Multiple Specifications
Product Name: O-chlorobenzaldehyde Request for quotation
CAS: 89-98-5
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228 Click to send a QQ message
Wechat: 13651600618
WhatsApp: +8613651600618
Orange Petrochemical (Zhejiang Free Trade Zone) Co., Ltd.
Product Name: 2-Chlorobenzaldehyde Request for quotation
CAS: 89-98-5
Tel:
Email: xiehao966@gmail.com
Mobile: 86 15032869000
View History
89-98-5
Raw Materials for 89-98-5
2-Chlorotoluene
2-Chlorotoluene
Chlorine
Downstream Products for 89-98-5
2-Chloro-5-nitrobenzaldehyde
Clofentezine
  • Home
  • Product Category

© 2015, 2023 ChemBK.com All Rights Reserved | Build: 20230617001