890839-29-9

890839-29-9 - Names and Identifiers

Name	tert-butyl 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate
Synonyms	-1H-indazole-1-carboxylate 1-Boc-6-indazoleboronic acid pinacol ester 1-Boc-1H-indazole-6-boronic acid pinacol ester 1-(tert-Butoxycarbonyl)-1H-indazole-6-boronic acid pinacol ester 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate tert-butyl 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate 1,1-dimethylethyl 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate 1H-Indazole-1-carboxylic acid, 6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-, 1,1-diMethylethyl ester
CAS	890839-29-9

890839-29-9 - Physico-chemical Properties

Molecular Formula	C18H25BN2O4
Molar Mass	344.21
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

890839-29-9 - Introduction

tert-butyl 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate, chemical name is tert-butyl 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate.

Nature:
-Appearance: Colorless or light yellow crystal
-Solubility: Soluble in some organic solvents, such as ethanol, dichloromethane
-melting point: about 78-82 ℃

Use:
tert-butyl 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate is a reagent commonly used in organic synthesis and is often used in the synthesis of indole compounds. It can be reacted with indole compounds by transesterification or other methods to introduce borate groups into the target compounds. This boronate group can be further reduced or reacted with other reagents for the synthesis of various organic compounds, such as pharmaceutical intermediates, biomarkers, etc.

Preparation Method:
tert-butyl 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate can be prepared by reacting indole with 4,4,5,5-tetramethyl-1,3,2-dioxaborolane. The specific synthesis method will involve chemical reaction conditions and experimental operations, which need to be carried out in the laboratory.

Safety Information:
tert-butyl 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate has no clear toxicity or pathogenicity report at present, but it is still necessary to comply with the safety operation specifications of general chemical experiments during use. During the operation, attention should be paid to wear protective equipment, such as laboratory gloves, goggles, etc., to avoid contact with skin and eyes. When storing and handling the compound, care should be taken to avoid ignition and contact with strong oxidizing agents to prevent possible fire or explosion.

Last Update：2024-04-09 02:00:48