89324-16-3

89324-16-3 - Names and Identifiers

Name	4-oxo-1,4-dihydropyridine-3-carbonitrile
Synonyms	LogP 4-Hydroxynicotinonitrile 4-hydroxynicotinonitrile 4-Hydroxy-3-pyridinecarbonitrile 4-hydroxypyridine-3-carbonitrile Nicotinonitrile, 4-hydroxy- (7CI) 3-Pyridinecarbonitrile, 4-hydroxy- 3-pyridinecarbonitrile, 4-hydroxy- 4-oxo-1,4-dihydropyridine-3-carbonitrile 3-pyridinecarbonitrile, 1,4-dihydro-4-oxo- 4-Hydroxy-1,4-dihydropyridine-3-carbonitrile
CAS	89324-16-3
InChI	InChI=1/C6H4N2O/c7-3-5-4-8-2-1-6(5)9/h1-2,4H,(H,8,9)

89324-16-3 - Physico-chemical Properties

Molecular Formula	C6H4N2O
Molar Mass	120.11
Density	1.27g/cm³
Boling Point	244.6°C at 760 mmHg
Flash Point	101.7°C
Vapor Presure	0.0302mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.571

89324-16-3 - Introduction

4-oxo-1 (4-oxo-1) is an organic compound with a chemical formula of C6H4N2O and a structural formula:

H
|
H3C-C(=O)N-C≡N

The following is a description of the properties, uses, preparation methods and safety information of the compound:

Nature:
-Appearance: A white or off-white solid
-Melting point: about 162-165°C
-Solubility: Soluble in most organic solvents, such as dimethyl sulfoxide, dimethyl formamide and methanol

Use:
- 4-oxo-1, is an important intermediate for the synthesis of a variety of drugs, especially for the synthesis of calcium ion antagonists.
-It can also be used to synthesize biologically active compounds, such as antibacterial agents and anti-tumor drugs.

Preparation Method:
A commonly used preparation method is obtained by reacting hydrogen cyanide with 2-aminopyridone under the catalysis of dimethyl sulfoxide (DMSO). The specific steps are as follows:
1. Dissolve 2-aminopyridone in DMSO.
2. Add hydrogen cyanide at low temperature and stir the reaction.
3. After the reaction is completed, the reaction solution is processed and purified to obtain 4-oxo-1, the product.

Safety Information:
- 4-oxo-1, no special safety problems are reported under normal use conditions.
-As an organic compound, use is subject to general laboratory safety practices, such as wearing appropriate personal protective equipment, avoiding inhalation, contact with skin, etc.
-When handling this compound or related compounds, care should be taken to prevent it from entering the eyes, mouth or inhalation, and avoid direct skin contact. If contact occurs, flush the affected area immediately with plenty of water and seek medical attention if you feel unwell.

Last Update：2024-04-09 02:00:49