894187-61-2
STF-118804
CAS: 894187-61-2
Molecular Formula: C25H23N3O4S
894187-61-2 - Names and Identifiers
894187-61-2 - Physico-chemical Properties
| Molecular Formula | C25H23N3O4S |
| Molar Mass | 461.53 |
| Density | 1.281±0.06 g/cm3(Predicted) |
| Melting Point | 187-190°C |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Appearance | Solid |
| Color | White to Off-White |
| pKa | 13.00±0.46(Predicted) |
| Storage Condition | Refrigerator |
| In vitro study | The IC50 values are in the nanomolar range STF-118804 reducing the activity of B- ALL cell lines containing the translation of the MLL chromosome. In addition, leukemic samples taken from five pediatric thallium patients were also sensitive to STF-118804 in the low nanomolar range. STF-118804 induced apoptosis in leukemic MV411 cells without prior cell cycle arrest. |
| In vivo study | STF-118804(25 mg/kg, twice daily, subcutaneously) increased survival in an orthotopic xenograft model of high-risk acute lymphoblastic leukemia and effectively depleted leukemia-initiated cells. |
894187-61-2 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.167 ml | 10.834 ml | 21.667 ml |
| 5 mM | 0.433 ml | 2.167 ml | 4.333 ml |
| 10 mM | 0.217 ml | 1.083 ml | 2.167 ml |
| 5 mM | 0.043 ml | 0.217 ml | 0.433 ml |
Last Update：2024-01-02 23:10:35
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Spot supply
Product Name: STF-118804 Visit Supplier Webpage Request for quotationCAS: 894187-61-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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