Name | Imiquimod (maleate) |
Synonyms | Imiquimod (maleate) IMiquiMod (Maleate) |
CAS | 896106-16-4 |
Molecular Formula | C18H20N4O4 |
Molar Mass | 356.3758 |
Solubility | 10 mM in DMSO |
Storage Condition | -20℃ |
In vivo study | In animal models, imiquimod stimulates the innate immune response by increasing NK cell activity, activating macrophages to secretecytokines and nitric oxide, and inducing proliferation and differentiation of B lymphocytes. Imiquimod stimulates the innate immune response through induction, synthesis, and release of cytokines, including interferon-a (IFN-α), interleukin (IL)-6, and tumour necrosis factor (TNF)-α. |