89787-12-2

89787-12-2 - Names and Identifiers

Name	(2-Isopropylphenyl)boronic acid
Synonyms	2-Isopropylphenylboronic 2-ISOPROPYLPHENYBORONIC ACID 2-Isopropylphenylboronic Acid 2-Isopropylphebylboronic acid 2-ISOPROPYLPHENYLBORONIC ACID 2-ISOPROPYLBENZENEBORONIC ACID 2-Isopropylbenzeneboronic acid (2-Isopropylphenyl)boronic acid [2-(1-methylethyl)phenyl]boronic acid Boronic acid, [2-(1-methylethyl)phenyl]- (9CI) 2-Cumylboronic acid~2-Isopropylphenylboronic acid
CAS	89787-12-2
InChI	InChI=1/C9H13BO2/c1-7(2)8-5-3-4-6-9(8)10(11)12/h3-7,11-12H,1-2H3

89787-12-2 - Physico-chemical Properties

Molecular Formula	C9H13BO2
Molar Mass	164.01
Density	1.04±0.1 g/cm3(Predicted)
Melting Point	85-86°C
Boling Point	297.2±33.0 °C(Predicted)
Flash Point	133.5°C
Vapor Presure	0.000616mmHg at 25°C
Appearance	White-like crystal
BRN	3090298
pKa	8.63±0.58(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.513
MDL	MFCD03411937

89787-12-2 - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36 - Wear suitable protective clothing.
HS Code	29319090
Hazard Class	IRRITANT

89787-12-2 - Introduction

(2-Isoppylphenyl) boronic acid is an organic compound with the chemical formula C9H13BO2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: White crystalline solid.
-Solubility: Soluble in organic solvents such as ethanol, dimethyl amide and dichloromethane, slightly soluble in water.
-Melting point: about 73-77°C.
-Stability: relatively stable under dry conditions, but may be damp in a humid environment.

Use:
- (2-Isopropylphenyl)boronic acid is an important organic boron compound, which has a wide range of applications in organic synthesis.
-It can be used as a ligand or reagent to participate in metal-catalyzed reactions, such as Suzuki-Miyaura coupling reactions.
-In the field of medicine, it can be used to synthesize drug intermediates and biologically active molecules, such as drugs, anti-tumor substances, etc.

Preparation Method:
- (2-Isopropylphenyl)boronic acid is generally obtained by reacting phenylboronic acid with 2-isopropyl phenol. The reaction is usually carried out under an inert atmosphere, and a solvent such as ethanol or methanol can be selected.
-The control of reaction temperature and time has an important effect on yield and purity.

Safety Information:
- (2-Isopropylphenyl)boronic acid may have an irritating effect on the skin, eyes and respiratory system. Immediately after contact, rinse with water for a large amount of time. Avoid inhalation and ingestion.
-During use and storage, avoid ignition and avoid contact with strong oxidants.
-Please refer to the Safety Data Sheet (MSDS) of the chemical for more detailed safety information.

Last Update：2024-04-09 02:00:49