9,19-CYCLO-9BETA-LANOST-24-EN-3BETA-OL
cycloartenol
CAS: 469-38-5
Molecular Formula: C30H50O
9,19-CYCLO-9BETA-LANOST-24-EN-3BETA-OL - Names and Identifiers
9,19-CYCLO-9BETA-LANOST-24-EN-3BETA-OL - Physico-chemical Properties
| Molecular Formula | C30H50O |
| Molar Mass | 426.73 |
| Density | 1.01±0.1 g/cm3(Predicted) |
| Melting Point | 115～117℃ |
| Boling Point | 505.5±19.0 °C(Predicted) |
| Solubility | Insuluble (1.3E-4 g/L) (25 °C) |
| Appearance | Powder |
| Color | White |
| BRN | 2224850 |
| pKa | 15.14±0.70(Predicted) |
| Storage Condition | -20°C Freezer |
| MDL | MFCD00200959 |
| In vitro study | Cycloartenol inhibits the proliferation and the colony formation potential of the glioma U87 cells in a concentration-dependent manner. The antiproliferative effects are found to be due to induction of Sub-G1 cell cycle arrest and triggering of apoptosis. Cycloartenol also causes significant alteration in the expression of Bax and Bcl-2. |
9,19-CYCLO-9BETA-LANOST-24-EN-3BETA-OL - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
9,19-CYCLO-9BETA-LANOST-24-EN-3BETA-OL - Reference Information
| biological activity | Cycloartenol is a phytosterol, it is one of the key precursors for the biosynthesis of many sterols. Cycloartenol inhibits the migration of glioma cells and inhibits the phosphorylation of p38 MAPK. Cycloartenol has anti-inflammatory, anti-tumor, antioxidant, antibacterial, anti-Alzheimer's disease and other pharmacological activities. Cycloartenol also plays an important role in plant growth and development. |
Last Update：2024-04-09 21:04:16
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