9-(1-Cyclopropylethyl)-N2-(2-(dimethylamino)ethyl)-N6-(3-(trifluoromethyl)benzyl)-9H-purine-2,6-diamine
NCC007
CAS: 2342583-66-6
Molecular Formula: C22H28F3N7
9-(1-Cyclopropylethyl)-N2-(2-(dimethylamino)ethyl)-N6-(3-(trifluoromethyl)benzyl)-9H-purine-2,6-diamine - Names and Identifiers
9-(1-Cyclopropylethyl)-N2-(2-(dimethylamino)ethyl)-N6-(3-(trifluoromethyl)benzyl)-9H-purine-2,6-diamine - Physico-chemical Properties
| Molecular Formula | C22H28F3N7 |
| Molar Mass | 447.5 |
| Density | 1.36±0.1 g/cm3(Predicted) |
| Boling Point | 573.5±60.0 °C(Predicted) |
| Appearance | Solid |
| pKa | 9.02±0.28(Predicted) |
| Storage Condition | 2-8°C，密封，干燥 |
| In vivo study | NCC007 (5-15 mM, infused into the lateral ventricle) controls circadian rhythms through CKI inhibition. Animal Model: Adult C57BL/6J background male mice (8 weeks old) Dosage: 5, 15 mM Administration: Infused into the lateral ventricle, constant dark condition Result: Showed more period lengthening effect with 0.15 hours at 5 mM and 15 mM. |
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