9-(2-Deoxy-2-fluoroarabinofuranosyl)guanine

9-(2-Deoxy-2-fluoroarabinofuranosyl)guanine - Names and Identifiers

Name	9-(2-Deoxy-2-fluoroarabinofuranosyl)guanine
Synonyms	2'-Deoxy-2'-fluoro-beta-D-arabinoguanosine 9-(2-deoxy-2-fluoroarabinofuranosyl)guanine 9-(2-Deoxy-2-fluoroarabinofuranosyl)guanine 9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)guanine 9-β-D-[2'-Fluoro-2'-deoxy-arabinofuranosyl]-guanin 9-β-D-[2'-Fluoro-2'-deoxy-arabinofuranosyl]-guanine 9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)guanine 2-amino-9-(2-deoxy-2-fluoro-D-arabinofuranosyl)-3,9-dihydro-6H-purin-6-one 6H-Purin-6-one, 2-amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-1,9-dihydro- 2-Amino-9-[(3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
CAS	103884-98-6
InChI	InChI=1/C10H12FN5O4/c11-4-6(18)3(1-17)20-9(4)16-2-13-5-7(16)14-10(12)15-8(5)19/h2-4,6,9,17-18H,1H2,(H3,12,14,15,19)/t3-,4+,6-,9?/m1/s1

9-(2-Deoxy-2-fluoroarabinofuranosyl)guanine - Physico-chemical Properties

Molecular Formula	C10H12FN5O4
Molar Mass	285.23
Density	2.17±0.1 g/cm3(Predicted)
Melting Point	275-279 °C
Boling Point	726.1±70.0 °C(Predicted)
Flash Point	392.9°C
Vapor Presure	3.94E-22mmHg at 25°C
pKa	12.68±0.70(Predicted)
Storage Condition	Room Temprature
Refractive Index	1.876

9-(2-Deoxy-2-fluoroarabinofuranosyl)guanine - Introduction

9-(2-Deoxy-2-fluoroarabinofuranyl) guanine is an organic compound with the chemical formula C≡≡H≡FN≡O, also known as 2-fluoroadeno-adenine (2-Fluoro-adenine). The following is a brief description of its nature, use, preparation and safety information:

Nature:
9-(2-deoxy-2-fluoroarabinofuranyl) guanine is a white solid with high thermal stability. It is a water-soluble compound that can be dissolved in water, alcohols and organic solvents.

Use:
9-(2-deoxy-2-fluoroarabinofuranyl) guanine is mainly used in drug research and synthesis. Guanine is an important nucleotide base involved in the synthesis and repair of DNA and RNA. By introducing a fluorine atom, the compound has particular application in the field of nucleic acid research and biomarkers.

Preparation Method:
9-(2-deoxy-2-fluoroarabinofuranyl) guanine can be obtained by chemical synthesis. The specific synthetic route involves a series of chemical reactions and steps, including functionalization reactions and substitution reactions. The specific experimental conditions for the preparation of the compound need to refer to the relevant professional literature or patent.

Safety Information:
The safety and toxicological properties of 9-(2-deoxy-2-fluoroarabinofuranyl) guanine have not been extensively studied. Appropriate laboratory safety measures should be taken during work to avoid contact with skin, eyes and mouth. Chemical protective gloves, goggles and protective clothing are required for operation. After any contact, the corresponding area should be rinsed with plenty of water immediately and seek the help of a doctor.

Last Update：2024-04-09 15:17:50