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9-Fluoropregna-1,4-diene-11,17,21-triol-3,20-dione17,21-diacetate

9-Fluoropregna-1,4-diene-11,17,21-triol-3,20-dione17,21-diacetate

CAS: 64088-99-9

Molecular Formula: C25H31FO7

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9-Fluoropregna-1,4-diene-11,17,21-triol-3,20-dione17,21-diacetate - Names and Identifiers

Name 9-Fluoropregna-1,4-diene-11,17,21-triol-3,20-dione17,21-diacetate
Synonyms 17,21-Diacetyloxy-9-fluoro-11-hydroxypregna-1,4-diene-3,20-dione
9-Fluoropregna-1,4-diene-11,17,21-triol-3,20-dione17,21-diacetate
11β-hydroxy-17α,21-diacetoxy-6α-fluoro-pregna-1,4-diene-3,20-dione
9-Fluoro-11,17,21-trihydroxypregna-1,4-diene-3,20-dione17,21-diacetate
Pregna-1,4-diene-3,20-dione, 17,21-bis(acetyloxy)-6-fluoro-11-hydroxy-, (6α,11β)-
CAS 64088-99-9

9-Fluoropregna-1,4-diene-11,17,21-triol-3,20-dione17,21-diacetate - Physico-chemical Properties

Molecular FormulaC25H31FO7
Molar Mass462.51
Physical and Chemical PropertiesChemical properties crystallization. Melting point 200 ℃.
UseThe use of the intermediate for the determination of the acetate.

9-Fluoropregna-1,4-diene-11,17,21-triol-3,20-dione17,21-diacetate - Production method

11 α,17 α,21-trihydroxypregnoster-4-ene-3 can be used, 20-dione (I. e. epihydrocortisone) is acetylated by (21-hydroxy), sulfonylated by (11-hydroxy) and eliminated [formation of 9(11)-double bond], (17 α-hydroxy) Acetylation, [9(11)-double bond hypobromic acid] addition, [9(11)-position] epoxidation, (epoxy hydrogen fluoride) addition, (1,2-position) dehydrogenation to obtain the product.

Last Update：2024-04-10 22:29:15
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9-Fluoropregna-1,4-diene-11,17,21-triol-3,20-dione17,21-diacetate
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