Name | fludrocortisone |
Synonyms | fludrocortisone 9alpha-fluorocortisol 9-alpha-fluorocortisol 9alpha-fludrocortisone 9alpha-fluoro-17-hydroxycorticosterone 9-alpha-fluoro-17-hydroxycorticosterone 9-fluoro-11,17,21-trihydroxypregn-4-ene-3,20-dione 9-fluoro-11beta,17,21-trihydroxy-pregn-4-ene-20-dione 9-fluoro-11-beta,17,21-trihydroxy-pregn-4-ene-20-dione 17,21-trihydroxy-20-dion(11beta)-pregn-4-ene-9-fluoro-11 (11beta)-9-fluoro-11,17,21-trihydroxypregn-4-ene-3,20-dione 9-alpha-fluoro-11-beta,17-alpha,21-trihydroxypregn-4-ene-3,20-dione (8xi,11beta,14xi)-9-fluoro-11,17-dihydroxy-3,20-dioxopregn-4-en-21-yl acetate |
CAS | 127-31-1 |
EINECS | 204-833-2 |
InChI | InChI=1/C23H31FO6/c1-13(25)30-12-19(28)22(29)9-7-16-17-5-4-14-10-15(26)6-8-20(14,2)23(17,24)18(27)11-21(16,22)3/h10,16-18,27,29H,4-9,11-12H2,1-3H3/t16?,17?,18-,20-,21-,22-,23-/m0/s1 |
Molecular Formula | C21H29FO5 |
Molar Mass | 380.45 |
Density | 1.1176 (estimate) |
Melting Point | 208-212°C |
Boling Point | 564.7±50.0 °C(Predicted) |
Specific Rotation(α) | D23 +139° (c = 0.55 in 95% ethanol) |
Flash Point | 301.6°C |
Water Solubility | 111mg/L(25 ºC) |
Solubility | DMSO (Slightly), Ethanol (Slightly, Heated), Methanol (Slightly, Sonicated) |
Vapor Presure | 1.27E-15mmHg at 25°C |
Appearance | Solid |
Color | White to Off-White |
pKa | 12.11±0.70(Predicted) |
Storage Condition | Refrigerator |
Refractive Index | 1.563 |
Hazard Symbols | Xn - Harmful |
Risk Codes | 63 - Possible risk of harm to the unborn child |
Safety Description | S22 - Do not breathe dust. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
Toxicity | LD50 intraperitoneal in mouse: 170mg/kg |