Name | xanthosine |
Synonyms | XANTHOSINE xanthosine XANTHINE RIBOSIDE Xanthosine dihydrate XANTHINE-9-RIBOFURANOSIDE 6-aMino-3-MethylpyriMidin-4(3H)-one 6-broMopyridin-3-yl isopropylcarbaMate 6-broMopyridin-3-yl diisopropylcarbaMate 9-pentofuranosyl-3,9-dihydro-1H-purine-2,6-dione 6-broMo-4-cyclopropyl-1,2-dihydropyrido[2,3-d]pyriMidine 6-benzyl-2,4-dihydroxy-5H-pyrrolo[3,4-d]pyriMidin-7(6H)-one |
CAS | 146-80-5 |
EINECS | 205-679-9 |
InChI | InChI=1/C10H12N4O6/c15-1-3-5(16)6(17)9(20-3)14-2-11-4-7(14)12-10(19)13-8(4)18/h2-3,5-6,9,15-17H,1H2,(H2,12,13,18,19)/t3-,5-,6-,9-/m1/s1 |
Molecular Formula | C10H12N4O6 |
Molar Mass | 284.23 |
Density | 2.25±0.1 g/cm3(Predicted) |
Melting Point | 174~176℃ |
Boling Point | 828.2°C at 760 mmHg |
Flash Point | 454.7°C |
Solubility | Soluble in hot water and hot dilute alcohol, slightly soluble in cold water, insoluble in ether. |
Vapor Presure | 4.6E-29mmHg at 25°C |
Appearance | White to white-like powder |
Color | White to Off-White |
Merck | 14,10065 |
pKa | pK1: |
Storage Condition | Hygroscopic, -20°C Freezer, Under inert atmosphere |
Sensitive | Easily absorbing moisture |
Refractive Index | -52 ° (C=8, 0.3mol/L |
MDL | MFCD00005726 |
Safety Description | 24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
HS Code | 29349990 |
Reference Show more | 1. [IF=4.072] Meng-zhen Zhou et al."Discovery and Biochemical Characterization of N-methyltransferase Genes Involved in Purine Alkaloid Biosynthetic Pathway of Camellia gymnogyna Hung T.Chang (Theaceae) from Dayao Mountain."Phytochemistry. 2022 Jul;199:113167 |
apply | xanthine nucleoside as an inhibitor of non-equilibrium cell dynamics division, which can not only realize the division mode of bone marrow mesenchymal stem cells from non-equilibrium to equilibrium The transition does not affect the characteristics of liver differentiation, which helps to improve the proliferation efficiency of bone marrow mesenchymal stem cells in vitro, and has a wide range of application space. |
Use | Xanthine nucleoside can be used to increase the production of caffeine by the fermentation of recombinant Corynebacterium glutamate. It is constructed with recombinant Corynebacterium glutamate as a fermentation strain for the production of caffeine. During the fermentation and culture process, a certain concentration of xanthine nucleoside is added to the fermentation, and the recombinant bacterial cells are subjected to permeability treatment by pressurization, promote the absorption of the substrate xanthine nucleoside by the recombinant bacteria, thereby increasing the fermentation yield of caffeine. |
biological activity | Xanthosine are nucleosides derived from xanthine and ribose. Xanthosine can increase the number of breast stem cells and milk production in cattle and goats. |