9-芴甲氧羰基-D-3-三氟甲基苯丙氨酸

9-芴甲氧羰基-D-3-三氟甲基苯丙氨酸 - Names and Identifiers

Name	Fmoc-D-3-Trifluoromethylphenylalanine
Synonyms	RARECHEM BK PT 0138 Fmoc-D-Phe(3-CF3)-OH FMOC-D-PHE(M-CF3)-OH FMOC-D-PHE(3-CF3)-OH FMOC-D-3-Trifluoromethylphe Fmoc-D-3-Trifluoromethylphe Fmoc-D-Phe(3-trifluoromethyl)-OH FMOC-D-PHE(3-TRIFLUOROMETHYL)-OH Fmoc-D-3-Trifluoromethylphenylalanine FMOC-3-(TRIFLUORMETHYL)-D-PHENYLALANIN Fmoc-3-Trifluoromethyl-D-phenylalanine FMOC-3-(TRIFLUOROMETHYL)-D-PHENYLALANINE N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-3-TRIFLUOROMETHYL-D-PHENYLALANINE (R)-2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-3-(3-TRIFLUOROMETHYL-PHENYL)-PROPIONIC ACID
CAS	205526-28-9

9-芴甲氧羰基-D-3-三氟甲基苯丙氨酸 - Physico-chemical Properties

Molecular Formula	C25H20F3NO4
Molar Mass	455.43
Density	1.351±0.06 g/cm3(Predicted)
Melting Point	140°C
Boling Point	611.2±55.0 °C(Predicted)
pKa	3.68±0.10(Predicted)
Storage Condition	Sealed in dry,2-8°C

9-芴甲氧羰基-D-3-三氟甲基苯丙氨酸 - Risk and Safety

Hazard Symbols	Xi - Irritant
WGK Germany	3
Hazard Class	IRRITANT

9-芴甲氧羰基-D-3-三氟甲基苯丙氨酸 - Introduction

Fmoc-D-3-Trifluoromethylphenylalanine is a chiral amino acid compound with the following characteristics and properties:

1. Nature: Fmoc-D-3-Trifluoromethylphenylalanine is a solid, with white or white appearance. It is stable at room temperature and relatively easy to dissolve in common organic solvents, such as dimethylformamide (DMF), dimethyl sulfoxide (DMSO) and so on.

2. Use: Fmoc-D-3-Trifluoromethylphenylalanine is mainly used for solid phase synthesis of protein and peptide synthesis. It is a commonly used chiral protecting group, which can be introduced into the target peptide chain by chemical synthesis method, and is used for the specific and orderly connection of amino acids in solid phase synthesis.

3. Preparation method: the synthesis method of Fmoc-D-3-Trifluoromethylphenylalanine is more complex, usually need to be synthesized by multi-step reaction. The specific preparation method can refer to the relevant chemical literature or patent.

4. Safety Information: during the use of Fmoc-D-3-Trifluoromethylphenylalanine, attention should be paid to its safe operation. This includes wearing appropriate personal protective equipment such as goggles, lab gloves and lab coats. In addition, it is necessary to operate in a well-ventilated environment and avoid contact with the skin and inhalation of its powder or vapor. If accidental contact or inhalation occurs, take timely countermeasures, such as flushing the affected area with plenty of water, and seek medical help if needed.

Last Update：2024-04-09 20:52:54