Name | 2-Hydroxybenzyl alcohol |
Synonyms | Saligenin Saligenol Salicylalkohol Salicyl alcohol MONOMETHYLOLPHENOL SALICYL ALCOHOL(RG) ,2-Dihydroxytoluene 2-Monomethylol phenol 2-Hydroxymethylphenol 2-hydroxybenzyl alcool 2-Hydroxybenzyl alcohol Salicyl alcohol~Saligenin Benzenemethanol, 2-hydroxy- 2-Hydroxy Benzyl Alcohol o-Hydroxy Benzyl Alcohol |
CAS | 90-01-7 |
EINECS | 201-960-5 |
InChI | InChI=1/C7H8O2/c8-5-6-3-1-2-4-7(6)9/h1-4,8-9H,5H2 |
Molecular Formula | C7H8O2 |
Molar Mass | 124.14 |
Density | 1,613 g/cm3 |
Melting Point | 83-85°C(lit.) |
Boling Point | 190.92°C (rough estimate) |
Flash Point | 133.7°C |
Water Solubility | 67 g/L (22 ºC) |
Solubility | Soluble in alcohol, ether, chloroform, propylene glycol, benzene and grease, insoluble in petroleum ether |
Vapor Presure | 0.00404mmHg at 25°C |
Appearance | Crystalline Flakes or Powder |
Color | Light beige |
Merck | 14,8325 |
BRN | 1907195 |
pKa | pK1:9.92 (25°C) |
Storage Condition | Store below +30°C. |
Stability | Stable. Incompatible with acids, acid chlorides, acid anhydrides, strong oxidizing agents. |
Sensitive | Sensitive to light |
Refractive Index | 1.5035 (estimate) |
MDL | MFCD00004617 |
Physical and Chemical Properties | White flake or needle-like crystals. Melting point 87 ℃, sublimation 100 ℃. Relative density 1.16(25 ℃). Soluble in alcohol, ether and chloroform, soluble in 15 parts of water, soluble in benzene, insoluble in petroleum ether. It is red when exposed to sulfuric acid. |
Use | For the pharmaceutical industry |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
WGK Germany | 3 |
RTECS | DO6430000 |
TSCA | Yes |
HS Code | 29072900 |
NIST chemical information | information provided by: webbook.nist.gov (external link) |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
biological activity | Salicyl alcohol is used as an intermediate in medicine, perfume and pesticide. |
Use | It is used as an intermediate for medicine, perfume and pesticide. used in the pharmaceutical industry |
production method | zinc acetate is added to the mixture of phenol and formaldehyde solution to adjust the pH to 5-6, the mixture was slowly heated to reflux for 1 hour, and the water and excess phenol were removed by vacuum distillation at a temperature not exceeding 100 °c. The residue in the kettle is stirred with carbon tetrachloride and then left to stand, and the precipitated salicylol is crystallized once with carbon tetrachloride to obtain the finished product. |