Molecular Formula | C10H21N3O |
Molar Mass | 199.29 |
Density | 1.0173 (rough estimate) |
Melting Point | 65-67℃ |
Boling Point | 127-129℃ (10 Torr) |
pKa | pKa 7.7 (Uncertain) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.4930 (estimate) |
Physical and Chemical Properties | Crystals. Melting point 47-49 ℃, boiling point 108.5-111 ℃(0.4kPa). |
Toxicity | LD50 intraperitoneal in mouse: 240mg/kg |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
Use | This product is an anti-filariasis drug, and the salt of the drug with the citric acid is the salt of the drug. As the antifilariant, the salts of diethylamine are also hydrochlorides and phosphates. Filariasis is caused by filariasis, a parasite in Human lymphatic or connective tissue. For the treatment and prevention of filariasis, the anti-insect effect is not ideal, and there are some adverse reactions, but compared with the existing anti-filariasis drugs, it is still the preferred drug. |
production method | the reaction of diethylamine with phosgene to produce diethylaminoformyl chloride, it is then condensed with perazine hexahydrate to give 1-diethylaminoformyl piperazine, which is finally methylated to give the product. |