9000-65-1
Gum tragacanth
CAS: 9000-65-1
Molecular Formula:
9000-65-1 - Names and Identifiers
| Name | Gum tragacanth |
| Synonyms | FEMA 3079 GUM SHIRAZ SHIRAZ GUM Tragant gum Astragalus gum Gum tragacanth GUM TRAGACANTH Gum tragacanth power TRAGACANTH GUM (ASTRAGALUS SPP.) |
| CAS | 9000-65-1 |
| EINECS | 232-552-5 |
9000-65-1 - Physico-chemical Properties
| Molar Mass | 840000 |
| Water Solubility | Slightly soluble in water. |
| Solubility | H2O: soluble20mg/mL |
| Appearance | powder |
| Color | Buff coloured powder |
| Odor | Odorless |
| Merck | 14,4581 |
| Storage Condition | Room Temprature |
| Stability | Stable. Incompatible with strong oxidizing agents. High levels of dust in the air create the risk of explosion. |
| MDL | MFCD00131255 |
| Physical and Chemical Properties | The unground astragalus gum system is flat or flake, usually curved fragments or straight or spiral twisted long fragments with a thickness of 0.5~2.5mm. White to pale yellow, translucent, horny tissue with short fissures. Odorless, tasteless, slimy palate. It is easier to crush when heated to 50 ℃. It is difficult to dissolve in water, but some astragalus gum (bassorin) is easy to absorb water and swell into gelatinous substances. 1g sample swelled into a smooth, thick, milky white gel-like substance in 50ml of water. The viscosity of astragalus gum solution is extremely high, the pH value is 5~6, the viscosity is the largest when the pH value is 5, and the pH value is stable to the viscosity (up to pH value of 2). After adding 1000 times of water and stirring, it will decompose into a neutral solution. Hydrolysis produces galacturonic acid, galactose, arabinose, xylose and fucose, and there may be small amounts of rhamnose and glucose (produced by trace amounts of starch and/or cellulose). Insoluble in ethanol, does not swell in 60%(w/V) ethanol aqueous solution. |
9000-65-1 - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 2 |
| RTECS | XW7750000 |
| TSCA | Yes |
| HS Code | 29400000 |
9000-65-1 - Reference
| Reference Show more | 1. Luo Wenjia, Wang Liping, Wu Jing, et al. To explore the mechanism of fukejing capsule in treating rats with chronic pelvic inflammatory disease from the correlation between "long-time disease entering collaterals" and Hemorheology and related cytokines. Pharmacology and clinical medicine. 2. Gong Jing ni, Yang Jin, Yuan Yi, et al. Rheological and textural properties of konjac glucomannan/tragacanth composite hydrogels [J]. Polymer Materials Science and Engineering, 2017(12). 3. Li Xiaoting Bai Yubin Li Bing et al. Study on the compatibility of excipients for compound suspension of pentachlorosamine and albendazole [J]. Animal and Veterinary Science v.51;No.407(06):57-62. 4. [IF = 6.429] Huang Lian et al."Effect of the added Polypropylene on the release of thyme essential oil and structure properties of chitosan based film." Food Packaging Shelf. 2020 Mar;23:100467 |
9000-65-1 - Nature
Open Data Verified Data
unmilled astragalus gelatine plate-like or flaky, 0. 5~2.5mm thick white to light yellow solid, odorless, tasteless, sticky and smooth in taste. Insoluble in water, insoluble in ethanol, in 60% ethanol water solution does not swell. When the pH value is 5, the viscosity is the largest.
Last Update：2024-01-02 23:10:35
9000-65-1 - Preparation Method
Open Data Verified Data
The coagulated substance naturally exuded from the long-cracked part of the trunk of the leguminous shrub plant astragalus was collected, or the coagulated substance was separated to promote its outflow of mucus, which was dried and pulverized after collection.
Last Update：2022-01-01 11:16:22
9000-65-1 - Standard
Authoritative Data Verified Data
The mucus extracted from the leguminous plant tragacanth in this line was obtained by drying.
Last Update：2024-01-02 23:10:35
9000-65-1 - Trait
Authoritative Data Verified Data
This product is a white or white-like translucent flat and curved ribbon-like sheet; The surface is parallel fine stripes; Hard, flat and smooth; Or white or white-like powder; Swells in water to form colloidal mucus.
Last Update：2022-01-01 11:22:03
9000-65-1 - Use
Open Data Verified Data
can be used as acidic food thickener, suspension emulsion, emulsifier and pharmaceutical adhesive. Can be used in food, cosmetics, printing and dyeing, leather and toothpaste, the general dosage of less than 2%. It can be used as a binder for tablets in the pharmaceutical industry.
Last Update：2022-01-01 11:16:23
9000-65-1 - Differential diagnosis
Authoritative Data Verified Data
- take an appropriate amount of this product, use 50% glycerol solution to load the tablet (General 2001), add 1 drop of zinc chloride iodine test solution Dropwise, and observe under a microscope. Round or oval starch granules are visible, the diameter was 4-10 μm, occasionally with 20PTM, most of which were single particles, occasionally with polymeric particles.
- take this product about O .lg, put in a centrifuge tube, add 2 m l of trifluoroacetic acid solution (6.7-l0), shake strongly to form a gel, plug, place 1 20V for 1 hour, centrifuge, the supernatant was transferred to a 5 0M l round-bottom flask, and 10ml of water was added. 60X: Rotary vacuum evaporation; The residue was dissolved by adding 90% methanol solution lm l and filtered, the filtrate was taken as the test solution; 10mg each of arabinose, rhamnose, xylose and galactose were added with 5ml of 90% methanol to dissolve, and the mixture was shaken to form a mixed reference solution. According to the thin layer chromatography (General 0502) test, Draw 5 ^ 1 of the test solution and the mixed reference solution, and point on the same silica gel G thin layer plate respectively, with 1.6% sodium dihydrogen phosphate solution-butanol-acetone (10 : 40 :50) as the developing solvent, the second development was carried out with the distance of about 10cm for the first time and about 15cm for the second time, spray with anisaldehyde solution (mix anisaldehyde 0.5ml, glacial acetic acid 10ml, methanol 85ml and sulfuric acid 5M l), uox: heat until spots show clear. In the chromatogram of the test sample, the spots of the same color appear at the corresponding positions of the chromatogram of the galactose, arabinose and xylose reference substances; spots of the same color should not be shown at the corresponding positions of the chromatogram of the rhamnose control.
- take about 0. 5 g of this product, soak with ethanol lm l, add 50ml of water in portions, and shake with it to form uniform mucus. Take 5ml of mucus and add 5ml and 4 ml of water. 5% barium hydroxide solution 2ml, shake, produce white flocculent precipitate, heating, solution and precipitate gradually yellow, add dilute hydrochloric acid 2 drops, shake, precipitate dissolution, solution fading.
Last Update：2022-01-01 11:22:04
9000-65-1 - Exam
Authoritative Data Verified Data
viscosity
take 9.0g of this product, plus gassing potassium 3. 0g, add water 3 0 0 m l, stir at 8 0 0 r /m I n for about 2 hours, until completely uniform dispersion and wetting, determination according to law (General Rule 0 6 3 3 Third method), with B r o o k f ie ldR V -D V type rotary viscometer, No. 5 rotor, 60 revolutions per minute, at 20°C ± 0. 1T: The viscosity should be 80% to 120% of the indicated viscosity.
foreign material
take 2.0g of this product, put it in a 250ml round-bottom flask, add 95ml of methanol to vortex to wet the sample, Add 60ml of hydrochloric acid solution (25-I00), add several grains of glass beads, after heating and refluxing in a water bath for 3 hours, the glass beads were removed, and the sample solution was filtered under reduced pressure with a constant weight G4 vertical melting funnel while hot. The round bottom flask was washed with a small amount of water and filtered, the residue was then washed with 40ml of methanol in portions and dried at 110 ° C. To constant weight. 0%.
ash
take the product l.O g, inspection according to law (General rule 2302), ash residue shall not exceed 4 .0%.
Heavy metals
The residue left under the ash extraction item shall be inspected according to law (General Principles 0821, second law) and shall not contain more than 20 parts per million of heavy metals.
microbial limit
This product shall be taken and inspected according to law (General Principles 1105 and 1106). The total number of aerobic bacteria per l g of test product shall not exceed lOOcfu, the total number of molds and yeasts shall not exceed lOOcfu, E. Coli should not be detected.
Last Update：2022-01-01 11:22:05
9000-65-1 - Category
Authoritative Data Verified Data
pharmaceutical excipients, adhesives, suspending agents and emulsifiers.
Last Update：2022-01-01 11:22:05
9000-65-1 - Storage
Authoritative Data Verified Data
sealed and stored in a dry place.
Last Update：2022-01-01 11:22:05
9000-65-1 - Reference Information
| FEMA | 3079 | TRAGACANTH GUM (ASTRAGALUS SPP.) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| apply | tragacanth, a thickener. Tragacanth is white to light yellow. Odorless, tasteless, sticky and smooth taste. Tragacanth in industrial applications: used as thickener, emulsifier, suspension, water-holding agent, film-forming agent; Tragacanth in food can be used as acidic oil-water system of emulsion stabilizer, such as: French, Russian salad dressing; and other kinds of sauce, sweet and sour sauce. |
| Introduction | tragacanth is a colorless, tasteless and edible natural macromolecule with sticky and smooth taste. Some of the components of Tragacanth are soluble in water to form a true solution; While the other component (tragacanth) is easy to absorb water and dissolve into a gel-like substance. 1% of the glue solution after full hydration is smooth, thick, milky white non-adhesive gel-like liquid. The greatest feature of tragacanth is that its gum properties are not affected at low acidity (pH<2 =. When used in oil-in-water emulsion stabilization system, there is no need to add other surfactants; Because tragacanth has the function of reducing the surface tension at the same time. Tragacanth has a very high solution viscosity; 1% concentration of the aqueous solution has a pseudoplastic fluid characteristics (with dilute mixing characteristics); It has a good advantage of pipeline transportation. Tragacanth is also insoluble in alcohol and other organic solvents and oils, the pH value of aqueous solution |
| uses | industrial applications: used as thickeners, emulsifiers, suspending agents, water-holding agents, film-forming agents. Pharmaceutical-for Cod Liver Oil, orange juice Cod Liver Oil, mineral oil, fat-soluble vitamins and other emulsion stabilizers. Pharmaceutical adhesive; Suspension stabilizer of insoluble particles; Suspension stabilizer (dosage: 0.2%). Cosmetics-high-grade cosmetics oil-water stability system, such as hair cream, face-to-face, etc. (0.4-0.8%) food-acidic oil-water system of emulsion stabilizer, such as: French, Russian salad dressing; and other kinds of cooking sauce, sweet and sour sauce, etc. thickener (especially for acidic foods); Stabilizer; Emulsifier. |
| identification test | solubility sample 1g in 50ml water should form smooth thick, milky white mucus, insoluble in ethanol, there was no swelling in 60%(w/V) ethanol. The aqueous suspension of the sample was observed with a microscope. There may be many rounded or irregularly scaly angular fragments; Starch granules below 25 μm in diameter; And lamellar cell membranes. When the iodinated zinc chloride solution was added, it turned purple. The sample should react with a saturated aqueous solution of copper acetate to produce a precipitate. Determined according to the method of identification test 3 in "Gum Arabic (10102). The sample stain is compared to a solution stain containing arabinose, xylose, fucose, galactose and galacturonic acid, which should be present but not mannose and uronic acid. |
| toxicity | ADI is not specified (FAO/WHO,2001). GRAS(FDA,§ 184.1351,2000). LD50 16400mg/kg (rat, oral). |
| usage limit | FDA,§ 184.1351(2000): baked goods 0.2%; Spices 0.7%; Various oils 1.3%; Sauce, sauce 0.8%; Meat products, 0.2%; Processed fruits and juices, 0.2%; Other foods 0.1%. FAO/EHO(1984,g/kg): mackerel and canned fish 20 (according to the filling soup); Processing cheese manufacturing 8, cream cheese 5; shannon cheese 5 (based on its cream mixture); Heat-treated flavored yogurt after fermentation 5000r/kg. It is also used for jelly, sauce, ice cream, salad sauce and candy. |
| production method | the secretion of leguminous plant gum Astragalus (Astra. A substance that naturally exudes and solidifies from the fractured part of the plant skin is collected, or it is separated to cause mucus to flow out. After collection, it is dried and pulverized. It is mainly produced in the mountainous areas of the Middle East. |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 21:11:58
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