9001-81-4
Phosphoglucomutase
CAS: 9001-81-4
Molecular Formula:
9001-81-4 - Names and Identifiers
9001-81-4 - Physico-chemical Properties
| Molar Mass | 62KDa（SDS-PAGE） |
| Density | 1.00g/mLat 20°C |
| Appearance | ammonium sulfate suspension |
| Storage Condition | -20°C |
| MDL | MFCD00131886 |
| Use | This product is for scientific research only and shall not be used for other purposes. |
9001-81-4 - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 1 |
| HS Code | 35079090 |
9001-81-4 - Introduction
Glucose phosphate mutase (EC 5.4.2.2) can catalyze the conversion of glucose 1-phosphate to glucose 6-phosphate. Glucose 1, 6-diphosphate is required as a coenzyme during the reaction.
Last Update：2022-10-16 17:41:02
9001-81-4 - Trait
White Flake crystalline powder.
Last Update：2023-08-16 21:32:38
9001-81-4 - Vitality definition
Catalytic conversion of 1.0 μmole α-d-glucose -1-phosphate to α-d-glucose -6-phosphate for 1 enzyme activity unit per minute at 30 ℃, pH 7.4
Last Update：2023-08-16 21:32:38
9001-81-4 - Source
Microorganism
Last Update：2023-08-16 21:32:38
9001-81-4 - Vitality
≥5 units/mg solid
Last Update：2023-08-16 21:32:38
9001-81-4 - Optimal PH
7.5～8.0
Last Update：2023-08-16 21:32:38
9001-81-4 - Isoelectric point
6.6
Last Update：2023-08-16 21:32:38
9001-81-4 - Optimum temperature
50℃
Last Update：2023-08-16 21:32:38
9001-81-4 - Thermal stability
＜55℃（PH7.4，15min）
Last Update：2023-08-16 21:32:38
9001-81-4 - PH stability
5.0～10.0
Last Update：2023-08-16 21:32:38
9001-81-4 - Specific vitality
≥150units/mg protein
Last Update：2023-08-16 21:32:38
9001-81-4 - Method of use
Resuspend the lyophilized powder in 0.25m glycyl glycine buffer, pH 7.4
Last Update：2023-08-16 21:32:38
9001-81-4 - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| Overview | Glucose phosphate mutase is also called glucose phosphate mutase. It is an enzyme that catalyzes the interconversion of glucose 1-phosphate (G-1-P) and glucose 6-phosphate (G-6-P). EC2.7.5.1. It is widely found in the muscle, brain, kidney, yeast and other microorganisms of animals, and has been purified from muscle. Glucose 1, 6-diphosphate (G-1,6-P) was used as coenzyme. The substrate can be phosphorylated by the coenzyme, and the coenzyme becomes the reaction product while the coenzyme is regenerated. This is related to the phosphorylation and dephosphorylation of the hydroxyl cycle of the serine residue in the enzymatic site. It has the same effect on ribose 1-phosphate and mannose 1-phosphate, but the activity is low. This enzyme can be activated by Mg2 , Mn2 Co2 cysteine, and is sensitive to fluoride, Cu2 ,Zn2 Pb2 ,Hg2 Ag2 and other inhibitors. |
| effect | glucose phosphate mutase (Phosphoglucomutase) is a group of important enzymes widely existing in human tissues. It can catalyze the mutual conversion of glucose -1-phosphate and glucose -6-phosphate, and plays an important role in sugar metabolism. |
| Use method | Re-suspend the freeze-dried powder in 0.25M Glycylglycine buffer with PH7.4. |
Last Update：2024-04-09 20:52:54
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