9025-13-2
Creatininase amidohydrolase
CAS: 9025-13-2
Molecular Formula:
9025-13-2 - Names and Identifiers
| Name | Creatininase amidohydrolase |
| Synonyms | CREATININASE Creatininase amidohydrolase creatininase from pseudomonas species creatininase from ochrobactrum anthropi |
| CAS | 9025-13-2 |
| EINECS | 232-786-8 |
9025-13-2 - Physico-chemical Properties
| Appearance | Morphological lyophilized powder |
| Storage Condition | 2-8°C |
| MDL | MFCD00130877 |
9025-13-2 - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-21 |
9025-13-2 - Reference
| Reference Show more | Note: part of our products can only provide part of the information, our company does not guarantee the authority of the information provided, only for the customer reference Exchange research. storage conditions: -20 ℃ Appearance: white powder Thermal stability: < 70 ℃ (pH 7.4, 30min) pH Stability: 8.5~9.0 (25 ℃, 16hr) optimal temperature: 70 ℃ optimal pH: 7.0~8.0 Isoelectric point: 4.7 Molecular weight: 175 kDa (Gel filtration) 29kD(SDS-PAGE) |
9025-13-2 - Specific activity
≥44units/mg solid.
Last Update：2023-08-16 21:32:38
9025-13-2 - Unit definition
One unit will convert one micromole of creatinine to creatine per min at pH 7.5 at 37℃.
Last Update：2023-08-16 21:32:38
9025-13-2 - Nature
| EPA chemical information | Creatininase (9025-13-2) |
Last Update：2024-04-10 22:29:15
9025-13-2 - Uses and synthesis methods
overview
Creatine Creatine is formed by dehydrating a molecule of water. Creatinine is excreted from urine by glomerular filtration and is an important indicator of glomerular function. Plasma creatinine concentration is determined by the production rate and excretion rate. The former is related to the metabolism of creatine and creatine phosphate, and the latter is related to the filtration function of the glomerulus, because it is no longer reabsorbed by the renal tubules after being filtered. The evaluation of kidney function is more specific than urea nitrogen. Commonly used alkaline picric acid method for determination. At present, there are commercial kits with good specificity and more suitable for automated enzymatic determination, and they have been popularized. Reference value (serum): picric acid method 27~71 μmol/L; Enzymatic method 3~54 μmol/L (male),44~97 μmol/L (female). Elevated creatinine is seen in renal insufficiency, severe muscle damage, muscular dystrophy, etc.; reduction is common in hypothyroidism and liver cirrhosis.
application
At present, there are two main types of creatinine enzymatic determination. One is the enzymatic kinetic determination to monitor the changes of creatinine immol hydrolase coupled glutamate dehydrogenase, and the other is the enzymatic kinetic determination to cause Trinder reaction between creatinine aminohydrolase coupled sarcosine oxidase and peroxidase. Among them, the latter is not affected by blood ammonia and other interfering substances due to the relatively low price of reagents. At present, there are a large number of commercial kits available.
Last Update：2024-04-09 21:01:54
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Product Name: Creatininase amidohydrolase Visit Supplier Webpage Request for quotationCAS: 9025-13-2
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Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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