90741-27-8

90741-27-8 - Names and Identifiers

Name	L-Proline, 5-oxo-1-(phenylmethyl)-, 1,1-dimethylethyl ester
Synonyms	1-Benzyl-5-oxo-L-proline tert-butyl ester (S)-tert-butyl 1-benzyl-5-oxopyrrolidine-2-carboxylate tert-Butyl (S)-1-benzyl-5-oxopyrrolidine-2-carboxylate 5-Oxo-1-(phenylmethyl)-L-proline 1,1-dimethylethyl ester tert-butyl (2S)-1-benzyl-5-oxo-pyrrolidine-2-carboxylate L-Proline,5-oxo-1-(phenylMethyl)-, 1,1-diMethylethyl ester L-Proline, 5-oxo-1-(phenylmethyl)-, 1,1-dimethylethyl ester
CAS	90741-27-8

90741-27-8 - Physico-chemical Properties

Molecular Formula	C16H21NO3
Molar Mass	275.34
Melting Point	73-74℃
Storage Condition	2-8°C

90741-27-8 - Introduction

L-Proline, 5-oxo-1-(phenylmethyl)-, 1,1-dimethylethyl ester, also known as L-proline tert-butyl ester, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Molecular formula: C17H23NO3
-Molecular weight: 293.37g/mol
-Appearance: White crystalline powder or solid
-Melting point: 85-87°C
-Boiling point: 437.5°C
-Solubility: Soluble in alcohol, ketone and ether, slightly soluble in water

Use:
- L-Proline, 5-oxo-1-(phenylmethyl)-, 1,1-dimethylethyl ester is widely used in the field of organic synthesis, especially in the fields of inorganic chemistry, medicinal chemistry and biochemistry.
-It can be used as a catalyst precursor for chiral catalysts, and can be used for asymmetric synthesis and preparation of chiral compounds.
-It can also be used for the preparation of drug intermediates and the synthesis of drug molecules.

Method:
L-Proline, 5-oxo-1-(phenylmethyl)-, 1,1-dimethylethyl ester can be synthesized by the following steps:
1. Condensation reaction of L-proline and tert-butyl alcohol was carried out under alkaline conditions to obtain L-proline tert-butyl ester.
2. transesterification of the obtained product with tert-butyl chloroformate to produce the final product L-Proline, 5-oxo-1-(phenylmethyl)-, 1,1-dimethylethyl ester.

Safety Information:
- L-Proline, 5-oxo-1-(phenylmethyl)-, 1,1-dimenthylethyl ester is generally safe under normal conditions of use, but appropriate safety measures still need to be taken.
-Wear protective gloves, goggles and protective clothing when using.
-Avoid contact with skin and eyes, such as accidental contact, immediately rinse with plenty of water. If you feel unwell, seek medical help.
-Avoid inhalation or ingestion of the substance.
-use or storage should be away from fire and high temperature environment.

Last Update：2024-04-09 15:18:00