913835-63-9

913835-63-9 - Names and Identifiers

Name	Imidazo[1,2-a]pyridine-6-boronic acid
Synonyms	3a-Azaindole-5-boricacid 9-Azoindole-5-boric acid 9-AZO-INDOLE-5-BORIC ACID 9-azo-indole-5-bronic acid 1H-indazol-3-ylboronic acid 6-Boronoimidazo[1,2-a]pyridine Imidazo[1,2-a]pyridin-6-boronic acid Imidazo[1,2-a]pyridine-6-boronic acid IMIDAZO[1,2-A]PYRIDINE-6-BORONIC ACID 98
CAS	913835-63-9
InChI	InChI=1/C7H7BN2O2/c11-8(12)7-5-3-1-2-4-6(5)9-10-7/h1-4,11-12H,(H,9,10)

913835-63-9 - Physico-chemical Properties

Molecular Formula	C7H7BN2O2
Molar Mass	161.95
Density	1.31±0.1 g/cm3(Predicted)
Melting Point	115-117
Boling Point	457°C at 760 mmHg
Flash Point	230.2°C
Vapor Presure	3.81E-09mmHg at 25°C
pKa	7.99±0.43(Predicted)
Storage Condition	Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.671

913835-63-9 - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Note	Irritant/Keep Cold

913835-63-9 - Introduction

Imidazo[1,2-a]pyridine-6-boronic acid is an organic compound whose chemical formula is C10H8BN3O2.

Nature:
1. Appearance: Imidazo[1,2-a]pyridine-6-boronic acid is a white solid.
2. Solubility: Soluble in common organic solvents, such as chloroform, dimethyl sulfoxide and dichloromethane, also soluble in water.

Use:
1. chemical reagent: Imidazo[1,2-a]pyridine-6-boronic acid is often used as a ligand for palladium-catalyzed reactions in organic synthesis and participates in organic synthesis reactions, such as substitution reactions and coupling reactions.
2. drug research: due to its special heterocyclic structure, Imidazo[1,2-a]pyridine-6-boronic acid is used in drug research and may have potential biological activity.

Method:
In general, the preparation method of Imidazo[1,2-a]pyridine-6-boronic acid is as follows:
1. First, indole and boric acid are reacted under alkaline conditions to obtain the corresponding indole borate ester.
2. Then, the indole borate ester is reacted with the corresponding nitrate under alkaline conditions to generate the Imidazo[1,2-a]pyridine-6-boronic acid.

Safety Information:
1. Imidazo the safety of [1,2-a]pyridine-6-boronic acid has not been fully evaluated, please pay attention to personal protective measures when using it and follow the laboratory safety operation regulations.
2. It may cause irritation to the eyes, skin and respiratory system, and direct contact should be avoided.
3. use should maintain good ventilation conditions, avoid inhalation of dust or vapor.
4. During use, avoid meeting with strong oxidants and strong acids to avoid dangerous reactions.
5. During storage and handling, it should be stored in a closed container, away from fire and high temperature.

Last Update：2024-04-09 21:01:54