915095-87-3
(S)-(2-Chloro-5-iodophenyl)(4-(tetrahydrofuran-3-yloxy)phenyl)methanone
CAS: 915095-87-3
Molecular Formula: C17H14ClIO3
915095-87-3 - Names and Identifiers
915095-87-3 - Physico-chemical Properties
| Molecular Formula | C17H14ClIO3 |
| Molar Mass | 428.65 |
| Density | 1.639 |
| Melting Point | 109-113oC |
| Boling Point | 526℃ |
| Flash Point | 272℃ |
| Solubility | Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly) |
| Appearance | Solid |
| Color | Off-White to Pale Beige |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
915095-87-3 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.333 ml | 11.665 ml | 23.329 ml |
| 5 mM | 0.467 ml | 2.333 ml | 4.666 ml |
| 10 mM | 0.233 ml | 1.166 ml | 2.333 ml |
| 5 mM | 0.047 ml | 0.233 ml | 0.467 ml |
Last Update：2024-01-02 23:10:35
915095-87-3 - Reference Information
| Overview | (2-chloro-5-iodophenyl)[4-[[(3S)] tetrahydro-3-furyl] oxy] phenyl] methanone belongs to ketone organic compounds, is a pharmaceutical intermediate, and can be used for preparing C- aryl glucoside SGLT2 inhibitors having the following general formula. This product is an intermediate of emparizine, a potent and selective SGLT-2 inhibitor that improves glycemic control syndrome in diabetic rats. |
| Application | (2-chloro-5-iodophenyl)[4-[[(3S)]-Tetrahydro-3-furyl] oxy] phenyl] methanone belongs to ketone organic compounds and can be used for the preparation of C- aryl glucoside SGLT2 inhibitors having the following general formula. SGLT2 is the major Na/glucose cotransporter in epithelial cells of the proximal tubule S1 segment and is responsible for 90% of glucose reabsorption in the kidney. SGLT2 inhibitors can inhibit renal glucose reabsorption, bring diabetic patients to normal plasma glucose levels through urinary glucose excretion, thereby increasing insulin sensitivity and delaying the development of diabetic complications. |
Last Update：2024-04-09 19:05:15
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Product Name: Empagliflozin Impurity 49 Visit Supplier Webpage Request for quotationCAS: 915095-87-3
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: (2-Chloro-5-iodophenyl)[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methanone Visit Supplier Webpage Request for quotation
CAS: 915095-87-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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CAS: 915095-87-3
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Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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