924869-20-5
1-(4-nitrophenyl)sulfonylpiperidin-4-one
CAS: 924869-20-5
Molecular Formula: C11H12N2O5S
924869-20-5 - Names and Identifiers
924869-20-5 - Physico-chemical Properties
| Molecular Formula | C11H12N2O5S |
| Molar Mass | 284.29 |
| Melting Point | 199-201°C |
924869-20-5 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
924869-20-5 - Introduction
1-(4-nitrophenyl)sulfonylpiperidin-4-one is an organic compound with the formula C13H13N3O4S. The following is its nature, use, preparation and safety information:
Nature:
1-(4-nitrophenyl)sulfonylpiperidin-4-one is a solid compound. It is a white crystalline powder with a distinctive smell. The compound is relatively stable at ambient temperature and soluble in organic solvents such as ethanol and dichloromethane.
Use:
1-(4-nitrophenyl)sulfonylpiperidin-4-one is commonly used as a reagent in organic synthesis. It can be used as an intermediate for the synthesis of other compounds, such as drugs, dyes and ligands. Due to its special structure, it has the potential to become a lead compound for antibiotics and antitumor drugs in the pharmaceutical field.
Preparation Method:
The preparation method of 1-(4-nitrophenyl)sulfonylpiperidin-4-one can react with 4-nitroaniline by benzenesulfonyl chloride to generate 1-(4-nitrobenzenesulfonyl) aniline. Then, the target product can be obtained by reacting 1-(4-nitrobenzenesulfonyl) aniline with barbituric anhydride.
Safety Information:
1-(4-nitrophenyl)sulfonylpiperidin-4-one need to follow certain safety procedures during use. It can cause irritation and damage to the eyes, skin and respiratory tract, so protective glasses, gloves and breathing equipment are required. During storage, it should be kept separate from flammable and explosive substances and avoid direct sunlight. At the same time, when handling this compound, it is necessary to follow the correct waste treatment method to ensure environmental safety.
Nature:
1-(4-nitrophenyl)sulfonylpiperidin-4-one is a solid compound. It is a white crystalline powder with a distinctive smell. The compound is relatively stable at ambient temperature and soluble in organic solvents such as ethanol and dichloromethane.
Use:
1-(4-nitrophenyl)sulfonylpiperidin-4-one is commonly used as a reagent in organic synthesis. It can be used as an intermediate for the synthesis of other compounds, such as drugs, dyes and ligands. Due to its special structure, it has the potential to become a lead compound for antibiotics and antitumor drugs in the pharmaceutical field.
Preparation Method:
The preparation method of 1-(4-nitrophenyl)sulfonylpiperidin-4-one can react with 4-nitroaniline by benzenesulfonyl chloride to generate 1-(4-nitrobenzenesulfonyl) aniline. Then, the target product can be obtained by reacting 1-(4-nitrobenzenesulfonyl) aniline with barbituric anhydride.
Safety Information:
1-(4-nitrophenyl)sulfonylpiperidin-4-one need to follow certain safety procedures during use. It can cause irritation and damage to the eyes, skin and respiratory tract, so protective glasses, gloves and breathing equipment are required. During storage, it should be kept separate from flammable and explosive substances and avoid direct sunlight. At the same time, when handling this compound, it is necessary to follow the correct waste treatment method to ensure environmental safety.
Last Update：2024-04-09 21:11:58
