Molecular Formula | C21H18N4O2 |
Molar Mass | 358.39 |
Density | 1.263±0.06 g/cm3(Predicted) |
Boling Point | 569.4±45.0 °C(Predicted) |
Solubility | DMSO : 250 mg/mL (697.56 mM; Need ultrasonic) |
pKa | 5.13±0.36(Predicted) |
Storage Condition | -20°C |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.79 ml | 13.951 ml | 27.903 ml |
5 mM | 0.558 ml | 2.79 ml | 5.581 ml |
10 mM | 0.279 ml | 1.395 ml | 2.79 ml |
5 mM | 0.056 ml | 0.279 ml | 0.558 ml |
biological activity | Manogepix (E1210, MGX, APX001A) is a broad-spectrum, orally active antifungal agent, it can inhibit Gwt1/Gwt1p (GPI anchored wall transfer protein 1), which plays an important role in fungal cell wall integrity. |
Target | Value |