Molecular Formula | C20H25N3O2 |
Molar Mass | 339.43 |
Solubility | DMSO: ≥15mg/mL |
Appearance | Yellow solid |
Color | white to beige |
Storage Condition | 2-8°C |
WGK Germany | 3 |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.946 ml | 14.731 ml | 29.461 ml |
5 mM | 0.589 ml | 2.946 ml | 5.892 ml |
10 mM | 0.295 ml | 1.473 ml | 2.946 ml |
5 mM | 0.059 ml | 0.295 ml | 0.589 ml |
biological activity | TC-H 106 (Pimelic diphylamide 106) is a slow, the tightly bound histone class I deacetylas (HDAC) inhibitors have Ki values of 148 nM, approximately 102 nM, and 14 nM for HDAC1, HDAC2, And HDAC3, respectively. |
Target | Value |
HDAC3 (Cell-free assay) | 14 nM(Ki) |
HDAC2 (Cell-free assay) | ~102 nM(Ki) |
HDAC1 (Cell-free assay) | 148 nM(Ki) |