939757-30-9

939757-30-9 - Names and Identifiers

Name	N-Boc-2-(2,4-dichlorophenyl)-2-hydroxyethanamine
Synonyms	N-Boc-2-(2,4-dichlorophenyl)-2-hydroxyethanaMine N-Boc-2-(2,4-dichlorophenyl)-2-hydroxyethanamine [2-(2,4-Dichloro-Phenyl)-2-Hydroxy-Ethyl]-Carbamic Acid Tert-Butyl Ester [2-(2,4-DICHLORO-PHENYL)-2-HYDROXY-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER [2-(2,4-Dichlorophenyl)-2-Hydroxyethyl]-Carbamic Acid 1,1-Dimethylethyl Ester [2-(2,4-DICHLOROPHENYL)-2-HYDROXYETHYL]-CARBAMIC ACID 1,1-DIMETHYLETHYL ESTER Carbamic acid, N-[2-(2,4-dichlorophenyl)-2-hydroxyethyl]-, 1,1-dimethylethyl ester
CAS	939757-30-9

939757-30-9 - Physico-chemical Properties

Molecular Formula	C13H17Cl2NO3
Molar Mass	306.18
Solubility	DCM, Ethyl Acetate
Appearance	Oil
Color	Colourless

939757-30-9 - Introduction

N-Boc-2-(2,4-dichlorophenyl)-2-hydroxyethanamine is an organic compound with the chemical formula C12H16Cl2NO3.

Nature:
-Appearance: Colorless or white crystalline solid.
-Solubility: Soluble in organic solvents such as ether, chloroform and dimethylformamide.
-Melting point: about 70-72 degrees Celsius.

Use:
The compound is often used in organic synthesis, as an intermediate to participate in a variety of chemical reactions. Specific uses include but are not limited:
-Drug research: can be used as a key intermediate for the synthesis of peptidomimetic drugs.
-Organic synthesis: Participate in reactions such as the construction of carbon-carbon bonds and the introduction of functional groups.

Method:
Generally, the preparation of N-Boc-2-(2,4-dichlorophenyl)-2-hydroxyethanamine can be carried out by the following steps:
1. The reaction of 2,4-dichlorobenzyl alcohol and dimethylformamide generates 2-(2,4-dichlorophenyl) acetamide.
2.2-(2,4-dichlorophenyl) acetamide and tert-butyl dimethylcarbamate (Boc2O) are reacted under the catalysis of a base to generate N-Boc-2-(2,4-dichlorophenyl)-2-hydroxyethanamine.

Safety Information:
-This compound may be harmful to health and may irritate the respiratory system, skin and eyes.
-When using or handling this compound, take protective measures, such as wearing protective glasses, gloves and dust masks.
-Keep away from heat sources, open flames and oxidants to avoid fire.
-When using or handling this compound, pay attention to a well-ventilated environment.

Last Update：2024-04-09 02:00:49