94-59-7
1-ALLYL-3,4-METHYLIDENEDIOXYBENZENE
CAS: 94-59-7
Molecular Formula: C10H10O2
94-59-7 - Names and Identifiers
94-59-7 - Physico-chemical Properties
| Molecular Formula | C10H10O2 |
| Molar Mass | 162.19 |
| Density | 1.099 g/mL at 20 °C |
| Melting Point | 11.2 °C(lit.) |
| Boling Point | 232-234 °C(lit.) |
| Flash Point | 208 °F |
| Water Solubility | insoluble, <0.1 g/100 mL at 18 ºC |
| Refractive Index | 0 |
| Physical and Chemical Properties | Colorless or yellowish liquid. The freezing point is about 11 °c, the boiling point is 232-234 °c, the relative density (20/4 °c) is 1.096, and the refractive index (nD20) is 1.5383. Soluble in alcohol, and chloroform, ether miscible, insoluble in water and glycerol. There is a smell of camphor wood. |
| Use | The chemical name of safrole is 4-allyl-1, 2-methoxyphenyl, which is one of the aroma components of green tea. Its use is as follows: Spices and perfume raw materials, as a perfume, used as a cheap soap perfume, eliminate the smell of the fat in the soap; As a raw material, the preparation of jasmine, vanillin and so on. |
94-59-7 - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R45 - May cause cancer R22 - Harmful if swallowed R68 - Possible risk of irreversible effects |
| Safety Description | S53 - Avoid exposure - obtain special instructions before use. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 3082 9/PG 3 |
94-59-7 - The natural source of safrole and its application in synthetic perfume
from VIP Journal Professional Edition
Author:
Abstract:
in eight kinds of Cinnamomum plant essential oil contains more safrole, including more than 90% of the content of Cinnamomum camphorata, cinnamon, Cinnamomum camphora, in this paper, the synthesis methods of seven kinds of spices, such as jasmine, concentrated fumvanillin and ethyl vanillin, from safrole are also introduced.
Key words:
safrole Cinnamomum plants Jasmine synthetic fragrance
DOI:
CNKI:SUN:XLXJ.0.1998-02-004
cited:
year:
1998
Last Update：2024-01-02 23:10:35
94-59-7 - Determination of safrole and 6-methyl coumarin in cosmetics by gas chromatography-mass spectrometry
from titanium academic
Author:
, Cai Tianpei , Wang Chao , Xiao Haiqing , Zhang Fan , Liu Liu
Abstract:
objective to establish a method for the determination of safrole, 6-methyl coumarin in cosmetics by gas chromatography-mass spectrometry. Methods the samples were extracted with methanol, ultrasonic volume, dehydration, filtered by 0.45μm filter membrane, with GC-MS method of qualitative, external standard method of quantitative. Results The recovery rate was 101.3% ~ 106.0%,RSD was 0.9% ~ 1.4% (safrole),0.9% ~ 2.1%(6-methyl coumarin), the limits of determination (S/N = 10) for safrole and 6-methylcoumarin were 5,10 μg/g, respectively. Conclusion The method has high accuracy and sensitivity, less sample consumption and short detection period. It has been applied to the determination of safrole and 6-methylcoumarin in cosmetics with satisfactory results.
Key words:
cosmetics gas chromatography-mass spectrometry safrole 6-methylcoumarin
DOI:
10.3969/j.issn.1001-5914.2007.05.030
cited:
year:
2007
Last Update：2023-08-16 22:05:47
94-59-7 - Research progress on analytical methods of coumarin and safrole compounds in food and cosmetics
from VIP Journal Professional Edition
Author:
Han Yi , Zhang Chengming , Yu Kun Meng Xia , Chen Yongkuan , MU Ming
Abstract:
The research status of the analysis methods of coumarin and safrole compounds in food and cosmetics at home and abroad in recent years were reviewed, the main problems of current analytical methods and the emphasis of future research are pointed out.
Key words:
coumarin safrole gas chromatograph liquid chromatography
DOI:
10.3969/j.issn.1000-4475.2013.01.012
cited:
year:
2013
Last Update：2023-08-16 22:05:47
94-59-7 - A preliminary study on safrole resources of black pepper
from hownet
Author:
process strength , Yu Xue Jian
Abstract:
Black pepper is a kind of resource rich in safrole, its leaves and fruit can extract aromatic oil, the analysis of dry leaf oil for 3.41-4.07% main component safrole content of 81.85%, and the origin of the same, with the development of planting and use of the value.
Key words:
hairy-leaf tree pepper introduction and cultivation sassafras oil safrole plant spice
DOI:
http://ir.kib.ac.cn:8080/handle/151853/11873
cited:
year:
1998
Last Update：2023-08-16 22:05:47
94-59-7 - Effect of safrole oxide on apoptosis and growth of vascular endothelial cells induced by removal of fibroblast growth factor
from VIP Journal Professional Edition
Author:
Miao Junying , Zhao Baoxiang , etc
Abstract:
Objective: to study the effect of safrole oxide on the apoptosis and growth of vascular endothelial cells induced by the removal of fibroblast growth factor (FGF). Methods: cell morphology was observed by light microscope; Cell growth was measured by MTT assay; DNA electrophoresis and fluorescence microscopy were used to detect DNA fragmentation; Cell cycle distribution was determined by flow cytometry. Results: The FGF-depleted vascular endothelial cells were treated with safrole oxide (5-25mg/L) for 24h. Cell spreading and growth were promoted, cell shedding and DNA fragmentation were inhibited, safrole oxide 10mg/L had no significant effect on cell cycle distribution. Safrole oxide 50-G2-M mg/L promotes the off-wall and DNA fragmentation of vascular endothelial cells, safrole oxide mg/L blocks the cell cycle in phase 2. Conclusion: safrole oxide inhibits the apoptosis of vascular endothelial cells at 10mg/L, but promotes the apoptosis at 100mg/L. Safrole oxide has an important effect on the growth and apoptosis of vascular endothelial cells.expand
Key words:
apoptosis umbilical vein vascular endothelium cell survival DNA fragment fibroblast growth factor
cited:
year:
2002
Last Update：2023-08-16 22:05:47
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