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943319-70-8

Ponatinib

CAS: 943319-70-8

Molecular Formula: C29H27F3N6O

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943319-70-8 - Names and Identifiers

Name Ponatinib
Synonyms CS-165
AP24534
AP-24534
Ponatinib
AP 24534
PONATINIB
AP24534(Ponatinib)
3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide
3-(IMIDAZO[1,2-B]PYRIDAZIN-3-YLETHYNYL)-4-METHYL-N-(4-((4-METHYLPIPERAZIN-1-YL)METHYL)-3-(TRIFLUOROMETHYL)PHENYL)BENZAMIDE
3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]benzamide
CAS 943319-70-8
EINECS 1308068-626-2

943319-70-8 - Physico-chemical Properties

Molecular FormulaC29H27F3N6O
Molar Mass532.56
Density1.3
Melting Point>175°C (dec.)
Solubility Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 25 mg/ml with warming).
AppearanceYellow powder.
ColorYellow
pKa12.99±0.70(Predicted)
Storage Condition-20°C
StabilityStable for 2 years from date? of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
UsePonatinib (AP24534) is a new and effective multi-target inhibitor acting on Abl, PDGFRα, VEGFR2, FGFR1 and Src. IC50 is 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM respectively.

943319-70-8 - Risk and Safety

HS Code29335990

943319-70-8 - Preparation solution concentration reference

 1mg5mg10mg
1 mM1.878 ml9.388 ml18.777 ml
5 mM0.376 ml1.878 ml3.755 ml
10 mM0.188 ml0.939 ml1.878 ml
5 mM0.038 ml0.188 ml0.376 ml
Last Update:2024-01-02 23:10:35
943319-70-8
Supplier List
Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: Ponatinib (AP24534) Visit Supplier Webpage Request for quotation
CAS: 943319-70-8
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Email: Int06@meryer.com
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MedChemExpress (MCE)
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CAS: 943319-70-8
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BOC Sciences
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CAS: 943319-70-8
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CAS: 943319-70-8
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SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Ponatinib (AP24534) Visit Supplier Webpage Request for quotation
CAS: 943319-70-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
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Shanghai Yuanye Bio-Technology Co., Ltd.
Spot supply
Product Name: Ponatinib (AP24534) Visit Supplier Webpage Request for quotation
CAS: 943319-70-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: Ponatinib (AP24534) Visit Supplier Webpage Request for quotation
CAS: 943319-70-8
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
MedChemExpress (MCE)
Multiple SpecificationsSpot supply
Product Name: AP24534 Visit Supplier Webpage Request for quotation
CAS: 943319-70-8
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
BOC Sciences
Spot supply
Product Name: Ponatinib Visit Supplier Webpage Request for quotation
CAS: 943319-70-8
Tel: +16314854226
Email: info@bocsci.com
Mobile: +16314854226
Linkedin: https://www.linkedin.com/company/boc-sciences
Product List: View Catalog
SKYRUN INDUSTRIAL CO.,LTD
Spot supply
Product Name: Ponatinib (with 4 ints.) Visit Supplier Webpage Request for quotation
CAS: 943319-70-8
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
Wechat: chinaskyrun
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Ponatinib (AP24534) Visit Supplier Webpage Request for quotation
CAS: 943319-70-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Shanghai Yuanye Bio-Technology Co., Ltd.
Spot supply
Product Name: Ponatinib (AP24534) Visit Supplier Webpage Request for quotation
CAS: 943319-70-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
943319-70-8
2-Sulphanilamido-4-methylpyrimidine
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