Name | Lucidenic acid B |
Synonyms | Lucidenic acid B (5alpha,7beta,12beta)-7,12-Dihydroxy-4,4,14-trimethyl-3,11,15-trioxo-chol-8-en-24-oic acid |
CAS | 95311-95-8 |
Molecular Formula | C27H38O7 |
Molar Mass | 474.58642 |
Melting Point | 179-181°C |
Boling Point | 676.3±55.0 °C |
Specific Rotation(α) | (c, 0.22 in MeOH)+169 |
Solubility | Soluble in methanol, chloroform. |
Appearance | White powder or crystal |
Color | White to Off-White |
Storage Condition | -20°C Freezer, Under inert atmosphere |
Plant Source: | Ganoderma lucidum |
biological activity | Lucidenic acid B is a natural product isolated from Ganoderma lucidum, which can induce apoptosis of tumor cells, activation of caspase-9 and caspase-3 and cleavage of PARP may result. Lucidenic acid B had no effect on cell cycle and had no effect on necrotic cells. |
Target | apotosis |