960203-28-5

960203-28-5 - Names and Identifiers

Name	1-[2-(2,4-DiMethylphenylsulfanyl)phenyl]piperazine Hydrochloride
Synonyms	Vortioxetine hydrochloride 1-(2-((2,4-Dimethylphenyl)thio)phenyl)piperazine hydrochloride 1-[2-(2,4-DiMethylphenylsulfanyl)phenyl]piperazine Hydrochloride
CAS	960203-28-5

960203-28-5 - Physico-chemical Properties

Molecular Formula	C18H23ClN2S
Molar Mass	334.90662
Storage Condition	Inert atmosphere,Room Temperature

960203-28-5 - Introduction

1-[2-(2,4-dimethylphenylsulfanyl) phenyl]piperazine Hydrochloride is a compound with the chemical formula C19H23ClN2S. The following are some information about the properties, uses, preparation and safety of this compound:

Nature:
-Appearance: Usually a white crystalline solid
-Melting Point: about 165-169 ℃
-Solubility: Soluble in water and some organic solvents

Use:
-Drug: 1-[2-(2,4-dimethylphenylsulfanyl) phenyl]piperazine Hydrochloride is an intermediate that can be used to synthesize some drugs, in particular drugs with antipsychotic and antidepressant activity.

Method:
The synthesis of -1-[2-(2,4-dimethylphenylsulfanyl) phenyl]piperazine Hydrochloride can generally be carried out by a stepwise reaction. First, 2,4-dimethylnitrobenzene is reacted with sulfuric acid to give 2,4-dimethylbenzenesulfonic acid. Then, 2,4-dimethylbenzenesulfonic acid is reacted with aniline and ethylenediamine to give 1-(2-((2,4-dimethylphenyl) thio) phenyl) piperazine. Finally, 1-(2-((2,4-dimethylphenyl) thio) phenyl) piperazine is reacted with hydrochloric acid to give 1-[2-(2,4-dimethylphenylsulfanyl) phenyl]piperazine Hydrochloride.

Safety Information:
- 1-[2-(2,4-dimethylsulfanyl) phenyl]piperazine Hydrochloride is a potentially toxic substance and should be handled with caution to avoid exposure.
-Follow safety practices when using or handling the compound, including wearing protective gloves, glasses, and protective clothing.
-During storage and transportation, it should be separated from combustibles, oxidants and strong acids.
-In case of accidental exposure or ingestion, seek medical help immediately and bring details of the compound.

Last Update：2024-04-09 21:01:54