Molecular Formula | C17H30N8O9 |
Molar Mass | 490.47 |
Density | 1.66±0.1 g/cm3(Predicted) |
Appearance | White to off-white lyophilized solid |
pKa | 2.85±0.10(Predicted) |
Storage Condition | -20°C |
In vitro study | Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3, with IC 50 of 5 μM. Gly-Arg-Gly-Asp-Ser-immobilized TiO2 nanotubes enhance osteoblast-like cell (MG-63) adhesion, and significantly increased cell spreading and proliferation. |
WGK Germany | 3 |
biological activity | Gly-Arg-Gly-Asp-Ser is a pentapeptide that forms the binding domain of glycoprotein, osteopontin and cells. |
target | IC50: 5 μM (αvβ3), 6.5 μM (αvβ5) |
in vitro study | Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3, with IC 50 of 5 μ m. Gly-Arg-Gly-Asp-Ser-immobilized TiO2 nanotubes enhance osteoblast-like cell (MG-63) adhesion, and significantly increased cell spreading and proliferation. |