Molecular Formula | C14H17NO3 |
Molar Mass | 247.29 |
Density | 1.14±0.1 g/cm3(Predicted) |
Boling Point | 396.0±34.0 °C(Predicted) |
Solubility | Chloroform, Dichloromethane |
Appearance | Solid |
Color | Light Brown |
pKa | 14.38±0.10(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Hazard Symbols | Xi - Irritant |
Hazard Class | IRRITANT |
Uses | 3-hydroxymethylindole-1-carboxylic acid tert-butyl ester is an important derivative and chemical synthesis intermediate, indole derivatives, Many natural substances with strong physiological activity are derivatives of indole. Many alkaloids also contain indole ring system. The commonly used antihypertensive drug reserpine is an important derivative of indole. |
Preparation | Preparation of 3-hydroxymethyl indole-1-carboxylic acid with indole -3-methanol and di-tert-butyl dicarbonate as starting materials tert-butyl ester. The synthesis reaction formula is as follows: |