A-(ISO-PROPYL)PHENYLACETONITRILE - Names and Identifiers
A-(ISO-PROPYL)PHENYLACETONITRILE - Physico-chemical Properties
Molecular Formula | C11H13N
|
Molar Mass | 159.23 |
Density | 0,967 g/cm3 |
Boling Point | 123-124°C 15mm |
Flash Point | 123-124°C/15mm |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.5050 |
A-(ISO-PROPYL)PHENYLACETONITRILE - Risk and Safety
Hazard Symbols | T - Toxic
|
Risk Codes | 20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
|
UN IDs | 3276 |
Hazard Class | 6.1 |
Packing Group | III |
A-(ISO-PROPYL)PHENYLACETONITRILE - Upstream Downstream Industry
A-(ISO-PROPYL)PHENYLACETONITRILE - Introduction
It is an organic compound with the chemical formula C12H15N.
Nature:
-Appearance: colorless liquid
-Melting point: About -20 ℃
-Boiling point: About 240 ℃
-Density: about 0.980 g/mL
Use:
It has important applications for organic synthesis and plays a key role in drug synthesis and pesticide synthesis.
Method:
It can be prepared by the following steps:
1. Acetophenone and 2-propyl magnesium bromide reaction, under alkaline conditions to generate 2-propyl -2-phenylethanol.
2. Nucleophilic Substitution of this product using sodium cyanide and diethyl dicarbonate.
3. Finally, it is dehydrated to obtain.
Safety Information:
It has low toxicity, but it is still necessary to pay attention to safety precautions during use to avoid skin contact and inhalation. At the same time, it is also a flammable liquid and should be kept away from fire and high temperature.
Last Update:2024-04-09 21:11:58