A-10338
PYRROLNITRIN
CAS: 1018-71-9
Molecular Formula: C10H6Cl2N2O2
A-10338 - Names and Identifiers
| Name | PYRROLNITRIN |
| Synonyms | 52230 pyroace A-10338 nsc-107654 pyrollnitrin PYRROLNITRIN 3-chloro-4-(3-chloro-2-nitrophenyl)-pyrrol PYRROLE,3-CHLORO-4-(3-CHLORO-2-NITROPHENYL)- 3-chloro-4-(2'-nitro-3'-chlorophenyl)pyrrole |
| CAS | 1018-71-9 |
| EINECS | 213-812-7 |
A-10338 - Physico-chemical Properties
| Molecular Formula | C10H6Cl2N2O2 |
| Molar Mass | 257.07 |
| Density | 1.5834 (rough estimate) |
| Melting Point | 124.5° |
| Boling Point | 410.5±45.0 °C(Predicted) |
| pKa | 14.28±0.50(Predicted) |
| Storage Condition | -20℃ |
| Refractive Index | 1.6100 (estimate) |
| In vitro study | Pyrrolnitrin (0-100 μg/ml) shows antibiotic activities against various bacteria and fungi with different MIC values. It against Staphylococcus aureus , Mycobacterium , Bacillus subtillis , Candida albicans , Aspergillus niger , and Trichophyton rubrum with MIC values of 50 μg/ml, 100 μg/ml, 0.78 μg/ml, 10 μg/ml, 12.5 μg/ml, and 1 μg/ml, respectively. Pyrrolnitrin (0-100 μg/ml) exhibits antimicrobial effect in a microtitre plate assay. It against Arthrobacter oxydans ATCC 14358, Bacillus coagulans ATCC 7050, Bacillus licheniformis ATCC 14580, Bacillus subtilis ATCC 6051, and Bacillus thuringiensis ATCC 10792 with MIC of 6.25 μg/ml. |
A-10338 - Risk and Safety
| Toxicity | LD50 in rats, rabbits (mg/kg): 68, 105 i.p. (Nishida) |
A-10338 - Reference Information
| biological activity | Pyrrolnitrin is an antibiotic (antibiotic) isolated from Pseudomonas pyrrolida. Pyrrolnitrin has a wide range of antibacterial activities against fungi, yeast and Gram-positive bacteria. |
| target | target: fungi, east and gram-positive bacteria |
| category | toxic substances |
| toxicity classification | poisoning |
| acute toxicity | oral-rat LD50: > 2000 mg/kg; Oral-mouse LD50: 1000 mg/kg |
| flammability hazard characteristics | thermal decomposition discharges toxic nitrogen oxides and chloride smoke |
| storage and transportation characteristics | warehouse low temperature ventilation and drying |
| fire extinguishing agent | water, carbon dioxide, foam, dry powder |
Last Update：2024-04-09 21:11:58
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CAS: 1018-71-9
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QQ: 3008007409
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CAS: 1018-71-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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