AC-DEVD-PNA
AC-ASP-GLU-VAL-ASP-PNA
CAS: 189950-66-1
Molecular Formula: C26H34N6O13
AC-DEVD-PNA - Names and Identifiers
| Name | AC-ASP-GLU-VAL-ASP-PNA |
| Synonyms | AC-DEVD-PNA AC-ASP-GLU-VAL-ASP-PNA AC-ASP-GLU-VAL-ASP-PARANITROANILIDE |
| CAS | 189950-66-1 |
AC-DEVD-PNA - Physico-chemical Properties
| Molecular Formula | C26H34N6O13 |
| Molar Mass | 638.58 |
| Density | 1.448±0.06 g/cm3(Predicted) |
| Boling Point | 1191.1±65.0 °C(Predicted) |
| Water Solubility | Soluble in water (partly), dimethyl sulfoxide, buffer, pH 7, and acetonitrile:methanol (1:1) (1 mg/ml). |
| Appearance | powder |
| Color | white |
| pKa | 2.97±0.10(Predicted) |
| Storage Condition | -20°C |
AC-DEVD-PNA - Risk and Safety
| WGK Germany | 3 |
AC-DEVD-PNA - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.566 ml | 7.83 ml | 15.66 ml |
| 5 mM | 0.313 ml | 1.566 ml | 3.132 ml |
| 10 mM | 0.157 ml | 0.783 ml | 1.566 ml |
| 5 mM | 0.031 ml | 0.157 ml | 0.313 ml |
Last Update：2024-01-02 23:10:35
AC-DEVD-PNA - Reference Information
| overview | currently, Ac-DEVD-pNA are mainly used to detect the activity of caspase-3 and caspase-7 in cells, and are also used to identify and evaluate caspase-3 and caspase-7 inhibitors and small molecule activators of procaspase-3/7. Its specific mechanism of action is: Caspase-3 or caspase-7 catalyze the hydrolysis of Ac-DEVD-pNA, and then release the starting color group p-nitroaniline. Through the detection of the color strength of p-nitroaniline, the activity of caspase-3 or caspase-7 in vivo is detected accordingly. |
| application | Ac-DEVD-pNA and Ac-DEVD-AMC are widely used in the fields of cell biology, chemical biology and medicinal chemistry. |
| biological activity | Ac-DEVD-pNA are ligands of caspase-3 and related cysteine proteases. |
Last Update：2024-04-09 21:54:55
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Spot supply
Product Name: AC-ASP-GLU-VAL-ASP-PNA Visit Supplier Webpage Request for quotationCAS: 189950-66-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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