ALL-RAC-ALPHA-TOCOPHEROL
DL-alpha-Tocopherol
CAS: 10191-41-0
Molecular Formula: C29H50O2
ALL-RAC-ALPHA-TOCOPHEROL - Names and Identifiers
| Name | DL-alpha-Tocopherol |
| Synonyms | A-TOCOPHEROL IRGANOX E 201 DL-α-Tocopherol ALPHA-TOCOPHEROLUM DL-alpha-Tocopherol ALPHA-DL-TOCOPHEROL 5,7,8-TRIMETHYLTOCOL ALL-RAC-ALPHA-TOCOPHEROL (2S)-2,5,7,8-tetramethyl-2-[(4S,8S)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-ol (2R)-2,5,7,8-tetramethyl-2-[(4R,8S)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-ol |
| CAS | 10191-41-0 |
| EINECS | 233-466-0 |
| InChI | InChI=1/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3/t21-,22+,29+/m0/s1 |
| InChIKey | GVJHHUAWPYXKBD-IEOSBIPESA-N |
ALL-RAC-ALPHA-TOCOPHEROL - Physico-chemical Properties
| Molecular Formula | C29H50O2 |
| Molar Mass | 430.71 |
| Density | 0.950g/mLat 20°C(lit.) |
| Melting Point | 2-4°C |
| Boling Point | 200-220°C 0,1mm |
| Specific Rotation(α) | [α]D20 - 0.02 - +0.02゜ (neat) |
| Flash Point | 240°C |
| Water Solubility | Miscible with chloroform, vegetable oils, ether, acetone and alcohol. Immiscible with water. |
| Solubility | Soluble in ethanol, chloroform, acetone and vegetable oil, insoluble in water |
| Vapor Presure | 4.59E-10mmHg at 25°C |
| Appearance | Transparent liquid |
| Color | Colourless to Dark Yellow to Thick |
| Merck | 14,9495 |
| BRN | 94012 |
| pKa | 11.40±0.40(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | Light Sensitive |
| Refractive Index | n20/D 1.506 |
| MDL | MFCD00006848 |
| Use | Antioxidants protect cells from oxidative stress or damage. |
ALL-RAC-ALPHA-TOCOPHEROL - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R39/23/24/25 - R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R11 - Highly Flammable |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37 - Wear suitable protective clothing and gloves. S16 - Keep away from sources of ignition. S7 - Keep container tightly closed. |
| UN IDs | UN1230 - class 3 - PG 2 - Methanol, solution |
| WGK Germany | 1 |
| RTECS | GA8746000 |
| FLUKA BRAND F CODES | 8-10-23 |
| TSCA | Yes |
| HS Code | 29362800 |
ALL-RAC-ALPHA-TOCOPHEROL - Reference
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ALL-RAC-ALPHA-TOCOPHEROL - Introduction
Almost odorless fat-soluble, easy to oxidize, dark color gradient deep.
Last Update：2022-10-16 17:11:31
ALL-RAC-ALPHA-TOCOPHEROL - Reference Information
| LogP | 12.2 at 25℃ |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| Introduction | DL-α-tocopherol, the chemical name is (±)-2,5,7,8-tetramethyl -2-(4 ', 8', 12 '-trimethyltridecyl)-6-color full alcohol, also known as vitamin E alcohol, is a class of compounds that mainly exhibit vitamin E activity. Because its vitamin activity was first identified in 1936 experiments on fecundity factors in rats, it was named "tocopherol". It is found in edible oil, fruits, vegetables and grains. It is a fat-soluble vitamin and an important antioxidant. The similar substances of DL-α-tocopherol are: d-α-tocopherol; d-α-tocopherol ester; dl-α-tocopherol ester; hydrogen succinate d-α-tocopherol ester; hydrogen succinate dl-α-tocopherol ester; β-tocopherol; γ-tocopherol; δ-tocopherol; tocopherol oil; all have the physiological activity of vitamin E, of which DL-α-tocopherol has the largest activity and the strongest antioxidant capacity. |
| source | natural vitamin e mainly exists in fruits and vegetables, nuts, lean meat, milk, eggs and pressed vegetable oil. 1. Fruits and vegetables: kiwi fruit, spinach, cabbage, vegetable stuffed flower, kale, lettuce, sweet potato, yam. 2. Nuts: almonds, hazelnuts and walnuts. 3. Squeezed vegetable oils: sunflower seeds, sesame seeds, corn, olives, peanuts, camellia, etc. in addition, safflower, soybean, cottonseed, wheat germ and cod liver oil all have a certain content of vitamin e, and wheat germ is the most abundant. |
| Discovery history | In 1922, American scientist Ivan discovered that the fertility of male white mice decreased, and female white mice were prone to abortion and lack of a fat-soluble substance. In 1938, the Swiss chemist Kara synthesized this substance and named it tocopherol, or vitamin E. Tocopherol can promote the secretion of sex hormones, increase the vitality and number of men's sperm; increase the concentration of female estrogen, improve fertility, and prevent abortion. It can also prevent and treat menopausal syndrome. |
| physiological function | vitamin e is a fat-soluble vitamin, also known as tocopherol or gestational phenol. it is a phenolic compound and is one of the most important antioxidants. it has the functions of anti-oxidation, promoting protein renewal and synthesis, regulating platelet adhesion and aggregation. the daily reference dosage of vitamin supplement for adults is vitamin a 1.5mg; Vitamin e is 30mg. there are many kinds of natural vitamin e. the structural difference is only in the side chains R1, R2 and R3, and exists in edible oil, fruits, vegetables and grain. it was successfully synthesized in 1988, can maintain the normal function of reproductive organs, has a good effect on the metabolism of the body, can make the ovaries weigh, promote its function, promote the maturation of follicles, and enlarge the corpus luteum, and can inhibit the oxidation of progesterone in the whole, thereby increasing the effect of progesterone. In addition, vitamin E has an adjuvant therapeutic effect on menorrhagia, vulvar pruritus, nocturnal calf spasm, and hemorrhoids. In recent years, vitamin E has been widely used in anti-aging. It is believed that it can eliminate the deposition of lipofuscin in cells, improve the normal function of cells, and slow down the aging process of tissue cells. |
| main efficacy | 1. vitamin e is a highly effective antioxidant, which can protect cell membranes from free radical damage and protect blood vessels, heart, breasts, eyes, skin, glands and other organs. So as to prevent a variety of chronic diseases. Such as breast cancer, cardiovascular disease, rectal cancer, etc. 2. Promote protein renewal and synthesis, which can promote wound healing. 3. Promote the proliferation of capillaries and small blood vessels, improve the surrounding blood circulation, increase the supply of oxygen in the tissue, and create good nutritional conditions for ulcer healing. 4. It is related to reproductive function and sperm production, preventing abortion, infertility and maintaining ovaries. 5. Protect erythrocyte membrane and prevent hemolytic anemia. 6. whitening and freckle removal, hairdressing and hair care, sunscreen and skin care. 7. Improve immune function and delay aging. 8. Inhibit the growth of Helicobacter pylori and reduce the recurrence rate after ulcer healing. |
| use | antioxidant to protect cells from oxidative stress or damage. (±)-α-tocopherol has been used to prepare mycobacterial emulsions, and has also been used to study immunomodulatory effects in influenza virus infection |
| Production method | Using 1,2, 4-trimethylbenzene as raw material, it is obtained by iodination, nitration, reduction, and oxidation to obtain 2,3, 5-trimethylbenzoquinone, then reduction, and condensation with chloroplast. |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 15:16:46
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Tel: 18301782025
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Mobile: 18021002903
QQ: 3008007409
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Multiple SpecificationsSpot supply
Product Name: All-rac-α-Tocopherol CRS Visit Supplier Webpage Request for quotationCAS: 10191-41-0
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
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