ALLOXAN
alloxan
CAS: 50-71-5
Molecular Formula: C4H2N2O4
ALLOXAN - Names and Identifiers
| Name | alloxan |
| Synonyms | ALLOXAN alloxan mesoxalylurea MESOXALYLUREA MESOXALYLCARBAMIDE Alloxan tetrahydrat Alloxan tetrahydrate ,4,5,6-Pyrimidinetetrone 2,4,5,6(1H,3H)-PYRIMIDINETETRONE pyrimidine-2,4,5,6(1H,3H)-tetrone Pyrimidine-2,4,5,6(1H,3H)-tetraone Pyrimidine-2,4,5,6(1H,3H)-tetraone monohydrate |
| CAS | 50-71-5 |
| EINECS | 200-062-0 |
| InChI | InChI=1/C4H2N2O4/c7-1-2(8)5-4(10)6-3(1)9/h(H2,5,6,8,9,10) |
ALLOXAN - Physico-chemical Properties
| Molecular Formula | C4H2N2O4 |
| Molar Mass | 142.07 |
| Density | 1.8588 (rough estimate) |
| Melting Point | ~245°C (dec.) |
| Boling Point | 259.59°C (rough estimate) |
| Flash Point | 201.4°C |
| Water Solubility | 8g/L(temperature not stated) |
| Vapor Presure | 2.05E-08mmHg at 25°C |
| pKa | pK (25°) 6.63 |
| Storage Condition | 2-8°C |
| Refractive Index | 1.4610 (estimate) |
| MDL | MFCD00149400 |
| Physical and Chemical Properties | Aleurea can form adduct with NaHSO3, react with HNO2 to form hydantoin, and be reduced to obtain bis-aleurea; alkaline hydrolysis of Mr Into a urea acid and then give acetone diacid and urea; And iron salt role is dark blue. |
| Use | Reagents for diabetes; inhibitors of mitochondrial aconitase, reagents for the determination of Ag, Cd, Co, Fe, HCN, Hg, Mg, Mn, Ni, Zn. |
ALLOXAN - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 8-10-23 |
ALLOXAN - Reference Information
| NIST chemical information | Information provided by: webbook.nist.gov (external link) |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| Introduction | Aurea is alloxan, and the appearance is a white orthorhombic crystal. It turns pink when exposed to air or heating above 230 ℃, and UVλmax243nm when pH6 in water. It often contains a crystal water, heated at 170 ℃ to become anhydrous, with a melting point of 256 ℃ (decomposition). Miscible with water, its hot aqueous solution is yellow, and becomes colorless after cooling, soluble in ethanol, acetone, glacial acetic acid, slightly soluble in chloroform, toluene, petroleum ether, acetic anhydride, insoluble in ether. The aqueous solution is acidic and touches the skin, turning the skin pale red with an unpleasant smell. It is present in dysentery mucus. Fig. 1 is the structural formula |
| Preparation method | Aurea is caused by the reaction of diurea and fuming nitric acid, or uric acid (2,6, 8-trihydroxypurine) is directly oxidized by nitric acid. It can also be obtained by the condensation of diethyl acetone diacid and urea. |
| Uses | Aurea can be used for biochemical research, organic synthesis, and also used as a chromogenic agent for iron, cobalt, nickel, and manganese plasma. It is used as an anti-tumor drug in medicine. |
| category | pesticide |
| toxicity classification | poisoning |
| acute toxicity | oral administration-rat LD50: 5210 mg/kg; Abdominal cavity-mouse LDL0:300 mg/kg |
| stimulation data | eyes-rabbit 500 mg/24 hours mild |
| explosive hazard characteristics | explosive; explosion occurs when heated over 170 ℃ |
| flammability hazard characteristics | combustible; decomposition of carbon dioxide at room temperature; combustion produces toxic nitrogen oxide smoke |
| storage and transportation characteristics | warehouse ventilation and low temperature drying; Store separately from food raw materials; Do not store in a sealed tank |
| fire extinguishing agent | dry powder, foam, sand, carbon dioxide, mist water |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 19:05:12
