AN-3485
AN-3485
CAS: 1213827-99-6
Molecular Formula: C14H13BClNO3
AN-3485 - Names and Identifiers
| Name | AN-3485 |
| Synonyms | AN-3485 [3-chloro-4-[(1-hydroxy-3H-2,1-benzoxaborol-6-yl)oxy]phenyl]methanamine 6-[4-(Aminomethyl)-2-chlorophenoxy]-2,1-benzoxaborol-1(3H)-ol hydrochloride |
| CAS | 1213827-99-6 |
AN-3485 - Physico-chemical Properties
| Molecular Formula | C14H13BClNO3 |
| Molar Mass | 289.52 |
| Appearance | Solid |
| Storage Condition | 2-8°C，密封，干燥 |
AN-3485 - Reference Information
| biological activity | AN-3485 is a benzoxaborole analog, Toll-Like Receptors(TLRs) inhibitors, IC50 in the range of 18~580 nM. |
| Target | IC50:AN-3485 inhibitors TLR2-, TLR3-, TLR4-, and TLR5-mediates, TNF-a, IL-1b, and IL-6 release with IC 50 values of human PBMCs (103±68 nM, 68±63 nM, 72±33 nM)and isolated monomers (77±26 nM; 18±6.7 nM; 32±6.5 nM) [1] . |
Last Update：2024-04-09 21:01:54
