Name | ARN-2966 |
Synonyms | 2-PMAP ARN-2966 ARN 2966 102212-26-0 ARN2966(2-PMAP) 2-((pyridin-2-ylmethyl)amino)phenol Phenol, 2-[(2-pyridinylmethyl)amino]- |
CAS | 102212-26-0 |
Molecular Formula | C12H12N2O |
Molar Mass | 200.24 |
Density | 1.241±0.06 g/cm3(Predicted) |
Melting Point | 130 °C(Solv: chloroform (67-66-3); hexane (110-54-3)) |
Boling Point | 354.4±27.0 °C(Predicted) |
Solubility | DMSO: ≥ 43.4 mg/mL |
pKa | 10.22±0.35(Predicted) |
Storage Condition | -20℃ |
Physical and Chemical Properties | Bioactive ARN2966 is an efficient post-transcriptional regulator of APP expression, which reduces the expression of APP but reduces the amount of Aβ. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 4.994 ml | 24.97 ml | 49.941 ml |
5 mM | 0.999 ml | 4.994 ml | 9.988 ml |
10 mM | 0.499 ml | 2.497 ml | 4.994 ml |
5 mM | 0.1 ml | 0.499 ml | 0.999 ml |
melting point | 130 °C(Solv: chloroform (67-66-3); hexane (110-54-3)) |
boiling point | 354.4±27.0 °C(Predicted) |
density | 1.241±0.06 g/cm3(Predicted) |
acidity coefficient (pKa) | 10.22±0.35(Predicted) |
biological activity | ARN2966 is an efficient post-transcriptional regulator for APP expression, reducing APP expression and thus reducing the amount of Aβ. |
biological activity | ARN2966 is an efficient, post-transcriptional regulator of APP expression, reducing APP expression but reducing the amount of Aβ. |