ARS-1323-ALKYNE

Name	ARS-1323-alkyne
Synonyms	ARS1323 Alkyne ARS-1323-alkyne ARS-1323-ALKYNE 3-((4-(4-Acryloylpiperazin-1-yl)-6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-2-yl)amino)-N-methyl-N-(prop-2-yn-1-yl)propanamide Propanamide, 3-[[6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-[4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-2-quinazolinyl]amino]-N-methyl-N-2-propyn-1-yl-
CAS	2436544-27-1

biological activity	ARS-1323-alkyne, a switch-II pocket (S-IIP) inhibitor, is a conformational-specific chemical reporter of KRASG12C nucleotide status in living cells.
target	KRAS(G12C)

Last Update：2024-04-09 20:44:15

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ARS-1323-ALKYNE