AS8351
N'-((2-hydroxynaphthalen-1-yl)methylene)isonicotinohydrazide
CAS: 796-42-9
Molecular Formula: C17H13N3O2
AS8351 - Names and Identifiers
| Name | N'-((2-hydroxynaphthalen-1-yl)methylene)isonicotinohydrazide |
| Synonyms | AS8351 AS 8351 NSC51355 NSC-51355 NSC 51355 N'-((2-hydroxynaphthalen-1-yl)methylene)isonicotinohydrazide N-[(Z)-(2-oxonaphthalen-1-ylidene)methyl]pyridine-4-carbohydrazide N'-[(2-hydroxynaphthalen-1-yl)methylidene]pyridine-4-carbohydrazide |
| CAS | 796-42-9 |
AS8351 - Physico-chemical Properties
| Molecular Formula | C17H13N3O2 |
| Molar Mass | 291.3 |
| Solubility | DMSO : 150 mg/mL (514.93 mM; Need ultrasonic and warming) |
| Appearance | solid |
| Color | Yellow |
| Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months. |
| In vitro study | AS8351 affects epigenetic modifications by competing with α-ketoglutarate (α-KG) for chelating iron [Fe(II)] in certain epigenetic enzymes, such as the JmjC domain-containing histone demethylases (JmjC-KDMs) that require α-KG and iron as co-factors. |
AS8351 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.433 ml | 17.164 ml | 34.328 ml |
| 5 mM | 0.687 ml | 3.433 ml | 6.866 ml |
| 10 mM | 0.343 ml | 1.716 ml | 3.433 ml |
| 5 mM | 0.069 ml | 0.343 ml | 0.687 ml |
Last Update：2024-01-02 23:10:35
AS8351 - Reference Information
| biological activity | AS8351 is a KDM5B inhibitor, active chromatin markers can be induced and maintained thereby promoting the production of cardiomyocyte-like cells. |
| Target | KDM5B |
Last Update：2024-04-09 21:32:10
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Product Name: N'-((2-hydroxynaphthalen-1-yl)methylene)isonicotinohydrazide Visit Supplier Webpage Request for quotationCAS: 796-42-9
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Spot supply
Product Name: N'-((2-hydroxynaphthalen-1-yl)methylene)isonicotinohydrazide Visit Supplier Webpage Request for quotationCAS: 796-42-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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