AZ6102
AZ6102
CAS: 1645286-75-4
Molecular Formula: C25H28N6O
AZ6102 - Names and Identifiers
AZ6102 - Physico-chemical Properties
| Molecular Formula | C25H28N6O |
| Molar Mass | 428.53 |
| Density | 1.31±0.1 g/cm3(Predicted) |
| Boling Point | 657.6±65.0 °C(Predicted) |
| Solubility | 10 mM in DMSO |
| pKa | 8.70±0.60(Predicted) |
| Storage Condition | -20℃ |
| In vitro study | AZ6102 is a potent dual TNKS1 and TNKS2 inhibitor, with IC 50 s of 3 nM and 1 nM, respectively. AZ6102 alao has 100-fold selectivity against other PARP family enzymes, with IC 50 s of 2.0 μM, 0.5 μM, and >3 μM, for PARP1, PARP2, and PARP6, respectively. AZ6102 shows Wnt pathway inhibition in DLD-1 cells. |
AZ6102 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.334 ml | 11.668 ml | 23.336 ml |
| 5 mM | 0.467 ml | 2.334 ml | 4.667 ml |
| 10 mM | 0.233 ml | 1.167 ml | 2.334 ml |
| 5 mM | 0.047 ml | 0.233 ml | 0.467 ml |
Last Update：2024-01-02 23:10:35
AZ6102 - Reference Information
| biological activity | AZ6102 is a potent dual inhibitor of TNKS1 and tnks2, the IC50 values were 3 nM and 1 nM, and the selectivity was 100 times higher than that for other PARP family proteins. The IC50 values for PARP1,PARP2 and PARP6 were 2.0 μm, 0.5 M and> 3 M. |
Last Update：2024-04-09 19:05:17
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Product Name: AZ6102 Visit Supplier Webpage Request for quotation
CAS: 1645286-75-4
Tel: 18301782025
Email: 3008007409@qq.com
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CAS: 1645286-75-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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