AZETIDIN-2-ONE
2-Azetidinone
CAS: 930-21-2
Molecular Formula: C3H5NO
AZETIDIN-2-ONE - Names and Identifiers
| Name | 2-Azetidinone |
| Synonyms | 2-Azetidone PROPIOLACTAM AZETAN-2-ONE 2-AZETIDINONE 2-Azetidinone AZETIDIN-2-ONE azetidin-2-one BETA-PROPIOLACTAM 2-Azacyclobutanone 2-AZACYCLOBUTANONE |
| CAS | 930-21-2 |
| InChI | InChI=1/C3H5NO/c5-3-1-2-4-3/h1-2H2,(H,4,5) |
AZETIDIN-2-ONE - Physico-chemical Properties
| Molecular Formula | C3H5NO |
| Molar Mass | 71.08 |
| Density | 1.0347 (rough estimate) |
| Melting Point | 74-76 °C (lit.) |
| Boling Point | 106 °C/15 mmHg (lit.) |
| Flash Point | 151.5°C |
| Solubility | chloroform: very soluble(lit.) |
| Vapor Presure | 0.102mmHg at 25°C |
| Appearance | Liquid |
| Color | Clear |
| BRN | 104563 |
| pKa | 15.86±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.4035 (estimate) |
| MDL | MFCD00013328 |
| Use | It was used in synthesis of optically pure densely functionalized γ-lactams. |
AZETIDIN-2-ONE - Risk and Safety
| Hazard Symbols | C - Corrosive |
| Risk Codes | 34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 3263 8/PG 2 |
| WGK Germany | 3 |
| TSCA | No |
| Hazard Note | Corrosive/Keep Cold |
| Hazard Class | 8 |
| Packing Group | III |
AZETIDIN-2-ONE - Introduction
2-Azetidinone(2-Azetidinone) is an organic compound with the chemical formula C3H5NO. Its molecule contains an azetidine structure, hence the name.
2-Azetidinone is a colorless crystal or white crystalline powder, soluble in many organic solvents such as ethanol, ether and ester. It has a high melting point and boiling point, and good stability at room temperature.
2-Azetidinone has a wide range of applications in organic synthesis. It is an important nitrogen heterocyclic compound, which can be used to synthesize other drugs, pesticides, photosensitive dyes and other organic compounds. In addition, it can be used as an intermediate of polymerization, a surfactant, an inhibitor of dye transferase, etc.
There are various methods for preparing 2-Azetidinone, and the common method is to hydrogenate 2-pyrrolidone. A specific step is to react 2-pyrrolidone with hydrogen in the presence of a catalyst, and a metal catalyst such as platinum or nickel is generally used for the reaction.
Regarding safety information, 2-Azetidinone is a chemical that can cause irritation to the skin, eyes and respiratory tract. When operating, you need to wear appropriate protective equipment, avoid contact with skin and eyes, and ensure that you operate in a well-ventilated environment. In addition, it should be stored away from fire and oxidizing agents.
2-Azetidinone is a colorless crystal or white crystalline powder, soluble in many organic solvents such as ethanol, ether and ester. It has a high melting point and boiling point, and good stability at room temperature.
2-Azetidinone has a wide range of applications in organic synthesis. It is an important nitrogen heterocyclic compound, which can be used to synthesize other drugs, pesticides, photosensitive dyes and other organic compounds. In addition, it can be used as an intermediate of polymerization, a surfactant, an inhibitor of dye transferase, etc.
There are various methods for preparing 2-Azetidinone, and the common method is to hydrogenate 2-pyrrolidone. A specific step is to react 2-pyrrolidone with hydrogen in the presence of a catalyst, and a metal catalyst such as platinum or nickel is generally used for the reaction.
Regarding safety information, 2-Azetidinone is a chemical that can cause irritation to the skin, eyes and respiratory tract. When operating, you need to wear appropriate protective equipment, avoid contact with skin and eyes, and ensure that you operate in a well-ventilated environment. In addition, it should be stored away from fire and oxidizing agents.
Last Update：2024-04-09 20:52:54
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