Ac-Leu-OH
N-Acetyl-L-leucine
CAS: 1188-21-2
Molecular Formula: C8H15NO3
Ac-Leu-OH - Names and Identifiers
| Name | N-Acetyl-L-leucine |
| Synonyms | AC-LEU-OH Ac-Leu-OH AC-LEUCINE AC-DL-LEU-OH N-acetylleucine ACETYL-L-LEUCINE AKOS BBS-00004735 ACETYL-DL-LEUCINE N-Acetyl-L-leucine IFLAB-BB F0777-0821 ACETYL-DL-LEUCINE, N- (2S)-2-(acetylamino)-4-methylpentanoate |
| CAS | 1188-21-2 |
| EINECS | 214-706-3 |
| InChI | InChI=1/C8H15NO3/c1-5(2)4-7(8(11)12)9-6(3)10/h5,7H,4H2,1-3H3,(H,9,10)(H,11,12)/p-1/t7-/m0/s1 |
Ac-Leu-OH - Physico-chemical Properties
| Molecular Formula | C8H15NO3 |
| Molar Mass | 173.21 |
| Density | 1.1599 (rough estimate) |
| Melting Point | 187-190°C(lit.) |
| Boling Point | 303.86°C (rough estimate) |
| Specific Rotation(α) | -24.5 º (c=4, MeOH) |
| Flash Point | 177.4°C |
| Water Solubility | 0.81 g/100 mL (20 ºC) |
| Solubility | Soluble in water (partly), ethanol (5%), and methanol. |
| Vapor Presure | 1.77E-06mmHg at 25°C |
| Appearance | Solid |
| Color | White |
| BRN | 1724849 |
| pKa | 3.67±0.10(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | -22 ° (C=5, EtOH) |
| MDL | MFCD00065131 |
| Physical and Chemical Properties | Melting point 190°C specific optical rotation -24.5 ° (c = 4, MeOH) water-soluble 0.81g/100 mL (20°C) |
Ac-Leu-OH - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| TSCA | Yes |
| HS Code | 29241900 |
| Hazard Class | IRRITANT |
Ac-Leu-OH - Reference Information
| NIST chemical information | Information provided by: webbook.nist.gov (external link) |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| introduction | N-acetyl-L-leucine is a white or white-like crystalline powder, soluble in water, and is mainly used as an organic intermediate. |
| use | N-acetyl-L-leucine is an important fine organic chemical intermediate, widely used in medicine, pesticide, chemical industry and other fields. Used as a biochemical reagent. |
| biological activity | N-acetyl-L-leucine is an effective endogenous metabolite that accelerates vestibular compensation after unilateral labyrinthectomy by acting in the cerebellum and thalamus. |
Last Update：2024-04-09 20:02:46
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